4394-10-9 Usage
Uses
Used in Pharmaceutical Industry:
2-[(4-ETHOXYPHENYL)AMINO]NICOTINIC ACID is used as an intermediate for the synthesis of various pharmaceutical products, contributing to the development of new medications.
Used in Research and Development:
In the field of research and development, 2-[(4-ETHOXYPHENYL)AMINO]NICOTINIC ACID serves as a building block for the creation of new compounds with potential medicinal properties, aiding in the advancement of pharmaceutical science.
Used in Biological Research:
2-[(4-ETHOXYPHENYL)AMINO]NICOTINIC ACID is used in biological research for studying its potential anti-inflammatory and antioxidant properties, which may lead to the discovery of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 4394-10-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,9 and 4 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4394-10:
(6*4)+(5*3)+(4*9)+(3*4)+(2*1)+(1*0)=89
89 % 10 = 9
So 4394-10-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H14N2O3/c1-2-19-11-7-5-10(6-8-11)16-13-12(14(17)18)4-3-9-15-13/h3-9H,2H2,1H3,(H,15,16)(H,17,18)
4394-10-9Relevant academic research and scientific papers
Synthesis of 2-(arylamino)nicotinic acids in high-temperature water
Li, Zhenghua,Xiao, Shangyou,Liang, Ronghui,Xia, Zhining
, p. 1691 - 1697 (2012/10/29)
In hydrothermal reactions at 150-180 °C, 2-(arylamino)nicotinic acids were synthesized by amination of 2-chloronicotinic acid with aromatic amine derivatives, with potassium carbonate as base. The procedure is efficient, environmentally friendly, and practical, with moderate to excellent yields (up to 98%). Springer Science+Business Media B.V. 2012.
Catalyst-free amination of 2-chloronicotinic acid in water under microwave irradiation
Li, Zheng-Hua,Xia, Zhi-Ning,Chen, Gang
experimental part, p. 709 - 711 (2012/03/09)
A simple, efficient and environmental friendly method for the synthesis of 2-arylaminonicotinic acids derivatives by reacting 2-chloronicotinic acid with anilines with potassium carbonate as the base and water as the media under microwave irradiation is described. The synthesis of 2-arylaminonicotinic acids is important because they are nonsteroidal anti-inflammatory drugs.
