4395-92-0

Usage

Uses

Used in Flavor Industry:
4-Isopropylphenylacetaldehyde is used as a flavoring agent for its unique citrus, bittersweet, and fruity flavor profile. It is commonly used in the production of food and beverages to enhance their taste and aroma.
Used in Fragrance Industry:
4-Isopropylphenylacetaldehyde is used as a fragrance ingredient for its characteristic bark-like scent. It is incorporated into perfumes, colognes, and other scented products to provide a distinct and appealing aroma.
Used in Chemical Synthesis:
4-Isopropylphenylacetaldehyde serves as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure and reactivity make it a valuable building block in organic synthesis.

Preparation

From cumyl magnesium chloride and ethyl formate or triethyl σ-formate followed by acid hydrolysis of the acetal.

InChI:InChI=1/C11H14O/c1-9(2)11-5-3-10(4-6-11)7-8-12/h3-6,8-9H,7H2,1-2H3

Upstream product

• 93805-69-7 trans-ethyl 3-(4-isopropylphenyl)oxirane-2-carboxylate 
• 122-51-0 orthoformic acid triethyl ester 
• 64-18-6 formic acid 
• 122-03-2 (4-isopropylbenzaldehyde) 

Downstream Products

• 10099-57-7 2-(4-isopropylphenyl)ethanol 
• 94995-86-5 6-chloro-3-(4-isopropyl-benzyl)-1,1-dioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide 
• 70090-66-3 1-isopropyl-4-prop-2-ynyl-benzene 

Relevant academic research and scientific papers

Biarylphosphonite gold(I) complexes as superior catalysts for oxidative cyclization of propynyl arenes into indan-2-ones

Striking gold: A series of variously functionalized propynyl arenes was smoothly converted into indan-2-ones by a new gold(I)-catalyzed oxidative cyclization process. [LAu]NTf2 (Tf=trifluoromethanesulfonyl) is a superior catalyst both in terms of yield and kinetics for the present transformation. Copyright

Functional fragrance precursor

The present invention relates to a class of fragrance precursor compounds comprising one or more of the compounds derived from the reaction of X—OH and an aldehyde or ketone, said fragrance precursor compounds being of the formula X—O—C(R) (R*) (OR**) wherein R is a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R* is H or a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R** is H or X; X—O representing a moiety derived from X—OH, and wherein X—OH is a compound selected from the group consisting of surfactants, fabric softeners, softener precursor ester amines, softener precursor amido amines, hair conditioners, skin conditions, saccharides and polymers. In a second aspect it relates to a method of preparing such precusors. Further the invention relates to compositions, comprising the precursor of the invention.

Precursors for fragrant ketones and fragrant aldehydes

The present invention refers to fragrance precursors of formula I for a fragrant ketone of formula II and one or more fragrant aldehydes or ketones of formula III and IV, These fragrance precursors are useful in perfumery, especially in the fine and functional perfumery.