439599-68-5

Upstream product

• 439599-66-3 5-benzyloxy-1-chloromethyl-7-[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetylamino]-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester 
• 286374-31-0 7-amino-5-benzyloxy-1-chloromethyl-1,2-dihydrobenzo[e]indole-3-carboxylic acid tert-butyl ester 

Downstream Products

• 439599-69-6 C₇₄H₇₇Cl₂N₁₁O₁₂ 
• 536738-70-2 C₆₆H₆₇Cl₂N₉O₁₁S 
• 536738-74-6 C₇₂H₇₃Cl₂N₁₁O₁₂S 
• 536738-72-4 C₇₂H₇₃Cl₂N₁₁O₁₂S 
• 633302-99-5 C₆₈H₇₂Cl₂N₁₂O₁₂ 

Relevant academic research and scientific papers

Synthesis and cytotoxicity evaluation of novel C7-c7, C7-N3 and N3-N3 dimers of 1-chloromethyl-5-hydroxy-1,2-dihydro-3H-benzo[e]indole (seco-CBI) with pyrrole and imidazole polyamide conjugates.

The C7-C7, C7-N3 and N3-N3 dimers of 1-chloromethyl-5-hydroxy-1,2-dihydro-3H-benzo[e]indole (seco-CBI) with pyrrole and imidazole polyamides were synthesized and preliminary anti-cancer evaluation carried out by NCI against three types of cancer cells.

Design and synthesis of bis 1-chloromethyl-5-hydroxy-1,2- dihydro-3H-benz[e]indole (seco-CBI)-pyrrole polyamide conjugates.

[carbohydrate structure: see text] The design and synthesis of bis 1-chloromethyl-5-hydroxy-1,2-dihydro-3H-benz[e]indole (seco-CBI)-pyrrole polyamide conjugates (13, 17) as DNA minor groove binding agents are described.