439614-40-1 Usage
Uses
Used in Medical Imaging:
NB-DOTA is used as a chelating agent for [application type] in positron emission tomography (PET) imaging for [application reason] its ability to form stable complexes with radioactive isotopes. This allows for the visualization of various biological processes and the detection of diseases in their early stages.
Used in Targeted Cancer Therapy:
In the field of targeted cancer therapy, NB-DOTA is used as a chelating agent for [application type] in the development of radiopharmaceuticals that can deliver targeted radiation doses to cancer cells for [application reason] its high stability and affinity for metal ions, particularly radioactive isotopes.
Used in Diagnosis and Treatment of Other Diseases:
Beyond cancer therapy, NB-DOTA is also utilized in the diagnosis and treatment of other diseases. It is used as a chelating agent for [application type] in the formation of complexes with metal ions for [application reason] its unique molecular structure and ability to chelate a variety of metals, enabling its use in a broad range of medical applications.
Used in Pharmaceutical Development:
In the pharmaceutical industry, NB-DOTA is used as a key component for [application type] in the development of novel radiopharmaceuticals for [application reason] its versatility in forming stable complexes with different metal ions, which can be tailored for specific therapeutic or diagnostic needs.
Check Digit Verification of cas no
The CAS Registry Mumber 439614-40-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,9,6,1 and 4 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 439614-40:
(8*4)+(7*3)+(6*9)+(5*6)+(4*1)+(3*4)+(2*4)+(1*0)=161
161 % 10 = 1
So 439614-40-1 is a valid CAS Registry Number.
439614-40-1Relevant academic research and scientific papers
Charbonniere, Loie J.,Weibel, Nicolas,Ziessel, Raymond F.
, p. 3933 - 3936 (2002)
A set of ligands bearing 6-bromo-2,2′-bipyridine pendant arms attached in the 5′-position are described. Transformation of the bromo to an ester was performed by a carboethoxylation reaction promoted by low-valent Pd(0), while saponification followed by acidification gave the acids. The introduction of an appended function 3-nitrobenzyl, benzamidomethyl, and tert-butylacetyl opens the way to further functionalize these scaffolds for potential labeling of biological material. The synthetic protocols represent a valuable approach to the rational design of ligands bearing oxophilic and anionic sidearms.
