439798-42-2Relevant academic research and scientific papers
Design and synthesis of a potent macrocyclic 1,6-napthyridine anti-human cytomegalovirus (HCMV) inhibitors
Falardeau, Guy,Lachance, Hugo,St-Pierre, Annie,Yannopoulos, Constantin G.,Drouin, Marc,Bedard, Jean,Chan, Laval
, p. 1693 - 1695 (2005)
A novel class of macrocyclic 1,6-napthyridines designed to adopt the presumed bioactive conformation of anti-HCMV acyclic 1,6-napthyridines are described. Both 14- and 15-membered macrocycles were shown to be highly potent against HCMV HSV-1 and HSV-2.
