439807-47-3Relevant academic research and scientific papers
An intramolecular Pauson-Khand approach to the synthesis of chiral cyclopentadienes
Rios, Ramon,Moyano, Albert,Pericàs, Miquel A
, p. 1023 - 1026 (2002)
A procedure for the synthesis of chirally-substituted cyclopentadienes has been developed by employing the intramolecular Pauson-Khand reaction of chiral amides derived from 8-nonen-2-ynoic acid. Hydride-mediated reduction of the resulting cyclopentenone adducts followed by acid-catalysed dehydration leads to the formation of the corresponding cyclopentadienes in good overall yield.
