439859-66-2

Upstream product

• 91-13-4 α,α'-dibromo-o-xylene 
• 131242-36-9 2-sulfanylpyrimidine 
• 612-12-4 o-Xylylene dichloride 

Downstream Products

• 439859-62-8 Cu₂((C₄H₃N₂SCH₂)2C₆H₄)3Cl⁽¹⁺⁾*ClO₄^(1-)=Cu₂((C₄H₃N₂SCH₂)2C₆H₄)3Cl(ClO₄) 
• 439859-60-6 Cu₂((C₄H₃N₂SCH₂)2C₆H₄)3ClO₄⁽¹⁺⁾*ClO₄^(1-)=Cu₂((C₄H₃N₂SCH₂)2C₆H₄)3(ClO₄)2 

Relevant academic research and scientific papers

IDO/TDO Inhibitor

A compound of formula (I) given below or a pharmaceutically acceptable salt of the compound is useful as an IDO/TDO inhibitor. Thus, the compound of formula (I) or the pharmaceutically acceptable salt of the compound can be used as, for example, a therapeutic agent for a disease or a disorder selected from tumor, infectious disease, neurodegenerative disorder, cataract, organ transplant rejection, autoimmune disease, postoperative cognitive impairment, and disease related to women's reproductive health [in the following formula (I), ring A represents an aromatic ring, an aliphatic ring, a heterocyclic ring, or a condensed ring of two or more rings selected from an aromatic ring, an aliphatic ring and a heterocyclic ring; X, R1 and R2 represent a substituent on a ring atom constituting ring A; m represents an integer of 0 to 6; X represents, for example, a halogen atom; and R1 and R2 are the same or different and are selected from, for example, the group consisting of groups of formula (a) or formula (b); and in the following formula (a) and formula (b), Y is selected from the group consisting of O, S, and Se, Z is selected from the group consisting of O, S, and Se, n represents an integer of 1 to 8, r represents an integer of 1 to 8, s represents an integer of 1 to 8, R4 represents, for example, —C(═NH)—HN2, and R6 represents, for example, a substituted or unsubstituted aryl group].

Assembly of silver(I) polymers with helical and lamellar structures

The new versatile multidentate nonchelating ligand 1,2-bis[(2-pyrimidinyl)-sulfanylmethyl]benzene (bpsb) was designed and prepared for supramolecular syntheses. Self-assembly between silver nitrate and the bpsb ligand resulted in the polymer [Ag4(bpsb)2-(NO3)4]n (1) with a single-stranded helical chain structure. Each bpsb ligand in 1 acts as a tetradentate ligand, in which two sulfur atoms and two nitrogen atoms from different pyrimidine groups coordinate to four Ag atoms in four different directions. The nitrate anions serve as a template for the formation of the helix and are either embedded in the interior of the helix or located in the flank of the helix. Self-assembly between silver perchlorate and the bpsb ligand under the same conditions gave rise to the polymer [Ag2(BpSb)3(ClO4)]n (2) comprising a two-dimensional lamellar network containing crownlike cavities. The silver atoms in two adjacent layers are arranged staggered in 2. The two-dimensional lamellar network comprising isolated cavities of [Ag6(bpsb)6] is very different from that of usual honeycomb structures.