439860-60-3

Basic information

• Product Name: trans-(4R,5R)-5-{4-[amino(benzyloxycarbonylimino)methyl]benzylaminocarbonyl}-2,2-dimethyl-1,3-dioxolane-4-carboxylic acid ethyl ester
• Synonyms: trans-(4R,5R)-5-{4-[amino(benzyloxycarbonylimino)methyl]benzylaminocarbonyl}-2,2-dimethyl-1,3-dioxolane-4-carboxylic acid ethyl ester
• CAS NO: 439860-60-3
• Molecular Weight: 483.521
• Mol File: 439860-60-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trans-(4R,5R)-5-{4-[amino(benzyloxycarbonylimino)methyl]benzylaminocarbonyl}-2,2-dimethyl-1,3-dioxolane-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: trans-(4R,5R)-5-{4-[amino(benzyloxycarbonylimino)methyl]benzylaminocarbonyl}-2,2-dimethyl-1,3-dioxolane-4-carboxylic acid ethyl ester(439860-60-3)
• EPA Substance Registry System: trans-(4R,5R)-5-{4-[amino(benzyloxycarbonylimino)methyl]benzylaminocarbonyl}-2,2-dimethyl-1,3-dioxolane-4-carboxylic acid ethyl ester(439860-60-3)

Safety Data

• Hazardous Substances Data: 439860-60-3(Hazardous Substances Data)

Upstream product

• 87-91-2 diethyl (2R,3R)-tartrate 
• 59779-75-8 diethyl (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dicarboxylate 

Relevant articles and documents

Synthesis of potential thrombin inhibitors. Incorporation of tartaric acid templates as P2 proline mimetics.

With the objective to prepare novel non-peptidic thrombin inhibitors, bioisosteres of the inhibitory tripeptide D-Phe-Pro-Arg chain have been examined. Thus, the P1 Arg was replaced with p-amidinobenzylamine, an elongated homologue of the same and with 2,