439912-01-3Relevant academic research and scientific papers
Stabilization of [(nBu2SnCl)(μ-Cl)2(ClSnnBu2)] within the solid-state structure of a Chlorodi-n-butyltin(IV) dithiocarbamate
Santacruz-Juárez, Ericka,Cruz-Huerta, Jorge,Torres-Huerta, Aarón,Hernández-Cruz, María G.,Barba, Victor,Tlahuext, Hugo,H?pfl, Herbert
, p. 121 - 129 (2014)
The combination of bis-dithiocarbamate ligands derived from N,N′-dibenzylcyclohexane-trans-1,4-diamine with dimethyl- and di-n-butyltin(IV) dichloride provided two discrete dinuclear complexes of the composition [(Me2SnCl)2(bis-dtc)]
Synthesis and antibacterial/antitubercular activity evaluation of symmetrical trans-cyclohexane-1,4-diamine derivatives
Kumar, Nitin,Kapoor, Ekta,Singh, Ramandeep,Kidwai, Saqib,Kumbukgolla, Widuranga,Bhagat, Sunita,Rawat, Diwan S
, p. 1441 - 1450 (2014/01/06)
A library of symmetrical trans-cyclohexane-1,4-diamine derivatives have been synthesized and evaluated for their activity against the M. tb H 37Rv strain. Most of the synthesized compounds show moderate to weak activity against M. tb H37Rv strain. Out of twenty-seven compounds tested, four compounds having substitution at p-position on the aromatic ring exhibit activity with MIC99 value ranging from 12.5 -25 μM. Compound 9u having i-propyl group substitution at p-position is found to be the most potent among all the tested compounds with MIC99 value of 12.5 μM against M. tb H37Rv strain. All these compounds have also been tested against Methicilin resistant Staphylococcus aureus (MRSA), and four of the compounds 9c, 9i, 9p and 9s possess good antibacterial activity with IC 50 ranging from 128 mg/L -256 mg/L.
Intramolecular trapping of an intermediate in the reduction of imines by a hydroxycyclopentadienyl ruthenium hydride: Support for a concerted outer sphere mechanism
Casey, Charles P.,Clark, Timothy B.,Guzei, Ilia A.
, p. 11821 - 11827 (2008/03/27)
Reduction of imines by [2,5-Ph2-3,4-Tol2(η 5-C4COH)]Ru(CO)2H (1) produces kinetically stable ruthenium amine complexes. Reduction of an imine possessing an intramolecular amine was studied to distinguish between inner sphere and outer sphere mechanisms. 1,4-Bn15NH(c-C6H10)=NBn (12) was reduced by 1 in toluene-d8 to give 85% of [2,5-Ph 2-3,4-Tol2(η4-C4CO)](CO) 2RuNHBn(c-C6H10)15NHBn (16-RuN, 15N), resulting from coordination of the newly formed amine to the ruthenium center, and 15% of trapping product [2,5-Ph2-3,4-Tol 2(η4-C4CO)](CO)2Ru 15NHBn(c-C6H10)NHBn (16-Ru15N,N), resulting from coordination of the intramolecular trapping amine. These results provide support for an outer sphere transfer of hydrogen to the imine to generate a coordinatively unsaturated intermediate, which can be trapped by the intramolecular amine. An opposing mechanism, requiring coordination of the imine nitrogen to ruthenium prior to hydrogen transfer, cannot readily explain the observation of the trapping product 16-Ru15N,N.
