439912-32-0

Basic information

• Product Name: propargyl pentafluorophenyl carbonate
• Synonyms: propargyl pentafluorophenyl carbonate
• CAS NO: 439912-32-0
• Molecular Weight: 266.124
• Mol File: 439912-32-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: propargyl pentafluorophenyl carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: propargyl pentafluorophenyl carbonate(439912-32-0)
• EPA Substance Registry System: propargyl pentafluorophenyl carbonate(439912-32-0)

Safety Data

• Hazardous Substances Data: 439912-32-0(Hazardous Substances Data)

Upstream product

• 35718-08-2 propargyl chloroformate 
• 771-61-9 2,3,4,5,6-pentafluorophenol 

Downstream Products

• 439912-50-2 3-phenyl-2-prop-2-ynyloxycarbonylamino-propionic acid 
• 439912-45-5 ((prop-2-yn-1-yloxy)carbonyl)-L-phenylalanine 
• 50903-52-1 (tert-butoxycarbonyl)-L-proline pentafluorophenol ester 
• 439912-40-0 (S)-3-Methyl-2-prop-2-ynyloxycarbonylamino-butyric acid pentafluorophenyl ester 
• 1252806-45-3 C₃₈H₃₁NO₁₁ 
• 1252806-46-4 C₃₈H₃₁NO₁₁ 
• 439912-39-7 (S)-3-Phenyl-2-prop-2-ynyloxycarbonylamino-propionic acid pentafluorophenyl ester 
• 50903-50-9 N-[(1,1-dimethylethoxy)carbonyl]-L-leucine pentafluorophenyl ester 

Relevant articles and documents

Simultaneous protection and activation of amino acids using propargyl pentafluorophenyl carbonate

A very efficient method for the simultaneous protection of the amino group and activation of the carboxyl group of amino acids is reported using propargyl pentafluorophenyl carbonate (PocOPfp). The amino group is protected as a propargyloxycarbonyl (Poc) derivative, and the carboxyl group is activated as a pentafluorophenyl ester. The yields obtained are good to excellent ranging from 60 to 87%.