439916-83-3

Upstream product

• 85-44-9 phthalic anhydride 
• 5680-83-1 N-(benzyloxycarbonyl)glycine hydrazide 
• 65138-05-8 (S)-2-hydroxy-3-methylbutyric acid benzyl ester 
• 439916-75-3 N'-(benzyloxycarbonyl)-N^β-phthaloylglycinehydrazide 

Downstream Products

• 439916-97-9 C₃₇H₅₁N₃O₁₁ 

Relevant academic research and scientific papers

Oligomerization of N-aminodipeptides: to the synthesis of heterogeneous backbone with 1:1 α:α-N-amino aminoacid residue patterns

A large number of N-aminodipeptides compounds have been obtained via a Mitsunobu protocol performed in solution or by solid-phase synthesis. The oligomerization of some of them has been studied in solution or on solid support leading to the formation of 1:1[α:α-N-amino]mers.

Original and efficient method for the preparation of N-aminoamide pseudodipeptides in high optical purity

N-Aminoamide pseudodipeptides ZAAΨ[CO-N(NPht)]-AAOR can be easily obtained via the Mitsunobu protocol by using α-hydroxyesters as alcohol partners and aminoacid phthaloyl hydrazide derivatives as acidic partners. The direct conversion of the phthaloyl group into tert-butyloxycarbonyl can be performed in a three-stage one-pot protocol.