439916-97-9

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 439916-83-3 (R)-2-[(2-Benzyloxycarbonylamino-acetyl)-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-amino]-3-methyl-butyric acid benzyl ester 
• 439916-75-3 N'-(benzyloxycarbonyl)-N^β-phthaloylglycinehydrazide 

Relevant academic research and scientific papers

Original and efficient method for the preparation of N-aminoamide pseudodipeptides in high optical purity

N-Aminoamide pseudodipeptides ZAAΨ[CO-N(NPht)]-AAOR can be easily obtained via the Mitsunobu protocol by using α-hydroxyesters as alcohol partners and aminoacid phthaloyl hydrazide derivatives as acidic partners. The direct conversion of the phthaloyl group into tert-butyloxycarbonyl can be performed in a three-stage one-pot protocol.