439926-88-2Relevant academic research and scientific papers
Amidinophenylalanine derivatives as thrombin inhibitors
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, (2008/06/13)
The compounds of the formula (formula 1) and pharmaceutically acceptable salts thereof and a process for preparing the same and pharmaceutical compositions containing the same are described wherein the substituents have the meaning as specified in the des
Thrombin inhibitors built on an azaphenylalanine scaffold
Zega, Anamarija,Mlinsek, Gregor,Solmajer, Tomaz,Trampus-Bakija, Alenka,Stegnar, Mojca,Urleb, Uros
, p. 1563 - 1567 (2007/10/03)
A series of azaphenylalanine derivatives were investigated as novel thrombin inhibitors based on the prodrug principle. By systematic structural modifications we have identified optimal groups for this series that led us to potent inhibitors of thrombin i
