440103-24-2Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of new phosphodiesterase type 4 inhibitors
Ochiai, Hiroshi,Odagaki, Yoshihiko,Ohtani, Tazumi,Ishida, Akiharu,Kusumi, Kensuke,Kishikawa, Katuya,Yamamoto, Susumu,Takeda, Hiroshi,Obata, Takaaki,Kobayashi, Kaoru,Nakai, Hisao,Toda, Masaaki
, p. 5063 - 5078 (2007/10/03)
The mode of interaction with enzyme is hypothesized based on the SAR data. The design, synthesis, and biological evaluation of new phosphodiesterase type 4 inhibitors, which possess new templates instead of a cyclohexane ring, are described. The mode of i
