440111-87-5

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 35978-33-7 ethyl 2-amino-4-(4-fluorophenyl)-thiophene-3-carboxylate 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 851853-31-1 [5-(4-fluorophenyl)-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-ylsulfanyl]acetic acid ethyl ester 
• 301687-15-0 5-(4-fIuorophenyl)-2-mercapto-3-phenyl-3H-thieno[2,3-d]pyrimidin-4-one 

Relevant academic research and scientific papers

Structure-activity relationship study of novel tissue transglutaminase inhibitors

Thieno[2,3-d]pyrimidin-4-one acylhydrazide derivatives were discovered as moderately potent inhibitors of TGase 2 (tissue transglutaminase) utilizing a fluorescence-based assay that measured TGase 2 catalyzed incorporation of the dansylated Lys derivative