440122-66-7 Usage
Uses
Used in Pharmaceutical Industry:
7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol is used as an anti-allergic drug for the treatment of various allergic conditions such as hay fever, hives, and allergic rhinitis. It functions by blocking the action of histamine, a substance in the body that triggers allergic symptoms including itching, sneezing, and a runny nose. 7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol's ability to act as a histamine H1 receptor antagonist and mast cell stabilizer makes it an effective therapeutic agent in managing allergic reactions.
As a Histamine H1 Receptor Antagonist:
7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol is used as a histamine H1 receptor antagonist to counteract the effects of histamine release during an allergic response. By binding to the H1 receptor, it prevents the receptor from being activated by histamine, thus reducing the severity of allergic symptoms.
As a Mast Cell Stabilizer:
In addition to its antagonistic properties, Bromoxin is also used as a mast cell stabilizer. This function helps to prevent the degranulation of mast cells, which are responsible for the release of histamine and other inflammatory mediators during an allergic reaction. By stabilizing mast cells, Bromoxin can reduce the overall inflammatory response and provide relief from allergic symptoms.
Check Digit Verification of cas no
The CAS Registry Mumber 440122-66-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,0,1,2 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 440122-66:
(8*4)+(7*4)+(6*0)+(5*1)+(4*2)+(3*2)+(2*6)+(1*6)=97
97 % 10 = 7
So 440122-66-7 is a valid CAS Registry Number.
440122-66-7Relevant academic research and scientific papers
Prodrug substituted benzoxazoles as estrogenic agents
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Page/Page column 28, (2010/10/20)
This invention provides estrogen receptor modulators of formula I, having the structure wherein Q, Q2, R1, R2, R2a, R3, R3a, and X as defined in the specification, or a pharmaceutically acceptable salt thereof.
Substituted benzoxazoles as estrogenic agents
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, (2008/06/13)
This invention provides estrogen receptor modulators of formula I, having the structure wherein R1, R2, R2a, R3, R3a, and R4, and X as defined in the specification, or a pharmaceutically acceptable salt thereof.
