440333-45-9

Upstream product

• 440333-17-5 (2R,3R,6R)-6-(tert-butyldiphenylsilanyloxy)-2,3-epoxy-3,7-dimethyloct-7-en-1-ol 
• 440333-58-4 (2S,3R,6R)-2-{3-(benzyloxy)propyl}-6-(tert-butyldiphenylsilyloxy)-3,7-dimethyloct-7-ene-1,3-diol 
• 440333-27-7 C₄₀H₅₄O₆Si 
• 440333-15-3 (2E,6R)-(+)-3,7-dimethyl-octa-2,7-diene-1,6-diol 
• 158512-40-4 (E)-(R)-8-(tert-Butyl-dimethyl-silanyloxy)-2,6-dimethyl-octa-1,6-dien-3-ol 
• 440333-44-8 (E)-(R)-6-(tert-Butyl-diphenyl-silanyloxy)-3,7-dimethyl-octa-2,7-dien-1-ol 

Downstream Products

• 440333-31-3 (2S,3R,6R)-3-acetoxy-2-(3-benzyloxypropyl)-6-chloro-3,7-dimethyl-7-octenyl acetate 
• 440333-33-5 C₂₅H₃₉ClO₄ 
• 1354928-48-5 (1'S,4'S,4a'S,5'R,6'R,8a'S)-5'-azido-4'-((2R,5S)-5-chloro-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)-6'-methyl-1-tosyloctahydro-2'H-spiro[aziridine-2,1'-naphthalen]-6'-ol 
• 1354928-74-7 C₂₇H₄₁ClN₂O₄S 
• 1354928-50-9 N-((1S,4S,4aS,5R,6R,8aS)-5-amino-4-((2R,5S)-5-chloro-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)-6-hydroxy-1,6-dimethyldecahydronaphthalen-1-yl)-4-methylbenzenesulfonamide 
• 91294-83-6 kalihinol-A 
• 440333-35-7 (2S)-5-benzyloxy-2-[(2R,5S)-(5-chloro-2,6,6-trimethyltetrahydropyran-2-yl)]-pentyl pivalate 

Relevant academic research and scientific papers

Total synthesis of antimalarial diterpenoid (+)-kalihinol A

Total synthesis of antimalarial diterpenoid (+)-kalihinol A, isolated from marine sponge Acanthella sp., is achieved. This total synthesis involves regioselective alkylation of an epoxide, construction of a tetrahydropyran ring by iodo-etherification, construction of a cis-decalin ring by intramolecular Diels-Alder reaction, isomerization of cis-decalin to trans-decalin, and subsequent functionalization of the trans-decalin ring.