440356-88-7Relevant articles and documents
Enantio-dependent binding and transactivation of optically active phenylpropanoic acid derivatives at human peroxisome proliferator-activated receptor alpha
Miyachi, Hiroyuki,Nomura, Masahiro,Tanase, Takahiro,Suzuki, Masahiro,Murakami, Koji,Awano, Katsuya
, p. 333 - 335 (2002)
Optically active phenylpropanoic acid derivatives [(S)-5, and (R)-5] were prepared, and their affinities for peroxisome proliferator-activated receptor (PPAR)α and PPARγ were evaluated. Binding assay and cell-based reporter assay indicated that the activi