440359-34-2

Upstream product

• 440359-26-2 methyl 3-O-benzyl-2,5-bis-O-di-tert-butylsilyl-α-D-arabinofuranoside 
• 440359-27-3 methyl 2,5-bis-O-di-tert-butylsilyl-α-D-arabinofuranoside 
• 440359-28-4 methyl 3-deoxy-2,5-bis-O-di-tert-butylsilyl-3-C-methylene-α-D-arabinofuranoside 
• 440359-25-1 methyl 3-O-benzyl-α-D-arabinofuranoside 
• 26532-10-5 methyl 2,3-anhydro-α-D-lyxofuranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 440359-33-1 methyl 3,6-di-O-(benzylidene acetal)-2,5-bis-O-tert-butylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside 
• 1054801-47-6 (1S,6R,8S,9R)-3,3-Di-tert-butyl-9-hydroxymethyl-8-methoxy-2,4,7-trioxa-3-sila-bicyclo[4.2.1]nonan-9-ol 

Downstream Products

• 440359-35-3 methyl 3,6-di-O-(benzylidene acetal)-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside 
• 440359-38-6 methyl 2,6-anhydro-5-O-benzoyl-3-C-hydroxymethyl-α-D-arabinofuranoside 
• 440359-36-4 methyl 2,6-anhydro-3-O-benzoyl-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside 
• 1053626-56-4 Benzoic acid (2R,3S,4S,5S)-3-bromomethyl-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-5-methoxy-tetrahydro-furan-3-yl ester 

Relevant academic research and scientific papers

Oligofuranosides containing conformationally restricted residues: Synthesis and conformational analysis

The synthesis of a panel of arabinofuranosyl oligosaccharide analogues (5-13) in which one ring is locked into either the E3 or oE conformation is described. The E3-locked scaffolds 15 and 16 required for the synthesis of 5-10 were prepared in one step from known 1,5-anhydroalditols. A number of routes were explored for the preparation of the oE-locked monosaccharide derivative 17 needed for the preparation of 11-13. The successful synthesis of 17 was achieved in 17 steps from D-arabinose. Subsequent analysis of 5-13 by 1H NMR spectroscopy demonstrated that the locked residue does not exert any detectable influence upon the conformers populated by adjacent conformationally unrestricted furanose rings.