4406-27-3 Usage
Uses
Used in Pharmaceutical Industry:
N-(2-CHLORO-BENZYL)-GUANIDINE is used as an active pharmaceutical ingredient for its antimicrobial properties, serving as an antibacterial and antifungal agent. It is incorporated into the development of medications targeting a range of microbial infections.
Used in Agrochemical Industry:
In the agrochemical sector, N-(2-CHLORO-BENZYL)-GUANIDINE is used as a component in the formulation of products designed to protect crops from bacterial and fungal diseases, thereby enhancing crop health and yield.
Used in Organic Chemistry:
N-(2-CHLORO-BENZYL)-GUANIDINE is utilized as a reagent in organic chemistry for facilitating various chemical transformations and reactions, contributing to the synthesis of complex organic molecules and compounds.
It is crucial to handle N-(2-CHLORO-BENZYL)-GUANIDINE with caution due to its potential toxicity and harmful effects if mismanaged.
Check Digit Verification of cas no
The CAS Registry Mumber 4406-27-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,0 and 6 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4406-27:
(6*4)+(5*4)+(4*0)+(3*6)+(2*2)+(1*7)=73
73 % 10 = 3
So 4406-27-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H22O5S/c1-14-10-12-17(13-11-14)27(23,24)26-18-15(2)20(22)25-19(21(18,3)4)16-8-6-5-7-9-16/h5-13,19H,1-4H3
4406-27-3Relevant academic research and scientific papers
Ligustrazine derivatives. Part 6: Design, synthesis and evaluation of novel ligustrazinyl acylguanidine derivatives as potential cardiovascular agents
Li, Zhenyu,Yu, Fang,Zhan, Peng,Shen, Yuemao,Liu, Xinyong,Cui, Lei,Wang, Shouxun
, p. 928 - 933,6 (2020/08/31)
A series of novel Ligustrazinyl acylguanidines was designed, synthesized and evaluated for their protective effect on injured vascular endothelial cell (ECV-304). The preliminary results demonstrated that some compounds possessed more potent activities than that of Ligustrazine in stimulating replication of the injured endothelial cell. Among the active compounds, compounds 8b, 8f and 8l displayed remarkable antioxidative activity with low EC50 values of 0.097, 0.059 and 0.094 mM, respectively. Structure-activity relationships were briefly discussed.
