441003-36-7

Upstream product

• 86364-02-5 2,6-dimethylphenyl trifluoromethanesulphonate 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 615-37-2 ortho-methylphenyl iodide 
• 1342307-11-2 2,6-dimethylphenyl 1H-imidazole-1-sulfonate 
• 576-26-1 2.6-dimethylphenol 

Downstream Products

• 1417574-52-7 N-(4-(2,6-dimethylphenyl)-2-methylbut-3-yn-2-yl)-4-methylbenzenesulfonamide 
• 1243249-31-1 2-((4-methoxyphenyl)ethynyl)-1,3-dimethylbenzene 
• 349667-94-3 (3E)-2-methoxy-2-methyl-4-(2,6-dimethylphenyl)-3-butene 
• 267644-39-3 (3Z)-2-methoxy-2-methyl-4-(2,6-dimethylphenyl)-3-butene 
• 267644-38-2 (3Z)-2-methyl-4-(2,6-dimethylphenyl)-2-triethylsiloxy-3-butene 
• 441003-43-6 (3E)-2-methyl-4-(2,6-dimethylphenyl)-3-buten-2-ol 
• 441003-37-8 (3Z)-2-methyl-4-(2,6-dimethylphenyl)-3-buten-2-ol 

Relevant academic research and scientific papers

Multimetallic Ir-Sn3-catalyzed substitution reaction of π-activated alcohols with carbon and heteroatom nucleophiles

An atom economic and catalytic substitution reaction of π-activated alcohols by a multimetallic IreSn3 complex has been demonstrated. The multimetallic IreSn3 complex can be easily synthesized from the reaction between [Cp*IrCl2]2 and SnCl2. In presence of as little as 1 mol % of the catalyst three different types of π-activated alcohols, namely benzyl, allyl, and propargyl alcohols, have been successfully transformed into alkylated products using carbon (arenes, heteroarenes, allyltrimethylsilane, and 1,3-dicarbonyls), nitrogen (sulfonamides), oxygen (alcohols), and sulfur (thiols) nucleophiles in very high yields. An electrophilic mechanism is proposed from the Hammett correlation study.

Microwave-promoted copper-free Sonogashira-Hagihara couplings of aryl imidazolylsulfonates in water

Aryl imidazol-1-ylsulfonates have been efficiently cross-coupled with aryl-, alkyl-, and silylacetylenes in neat water under copper-free conditions at 110 °C assisted by microwave irradiation. Using 0.5mol% of an oxime palladacycle as precatalyst, 2-dicyclohexylphosphino-2′,6′- dimethoxybiphenyl (SPhos, 2mol%) as ligand, hexadecyltrimethylammonium bromide (CTAB) as additive, and triethylamine (TEA) as base, a wide array of disubstituted alkynes has been prepared in good to high yields in only 30min. Copyright

Highly activated vinyl hydrogen in a significantly twisted styrene

(Chemical Equation Presented) The novel example of a vinylic hydrogen more reactive than a benzylic hydrogen was found by treatment of a twisted styrene derivative with a strong base followed by D2O quenching. In this paper, the full details of

Vinyl hydrogen more reactive than benzyl hydrogen toward base in significantly twisted styrenes

The novel example of vinyl hydrogen more reactive than benzylic hydrogen was found by treatment of a twisted styrene derivative with a strong base followed by D2O quenching. The characteristic nature of the vinyl hydrogen, which is activated by