4414-87-3

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine-3-acetonitrile
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine-3-acetonitrile;3-(Cyanomethyl)pyrrolo[2,3-b]pyridine;2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)
• CAS NO: 4414-87-3
• Molecular Formula: C₉H₇N₃
• Molecular Weight: 157.18
• Mol File: 4414-87-3.mol
• Article Data: 9

Chemical Properties

• Melting Point: 144 °C(Solv: benzene (71-43-2))
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.295g/cm³
• Refractive Index: 1.684
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 6.95±0.20(Predicted)
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine-3-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine-3-acetonitrile(4414-87-3)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine-3-acetonitrile(4414-87-3)

Safety Data

• Hazardous Substances Data: 4414-87-3(Hazardous Substances Data)

Usage

Description

1H-Pyrrolo[2,3-b]pyridine-3-acetonitrile is a chemical compound that belongs to the class of organic compounds known as pyrrolobenzodiazepines. These are polycyclic aromatic compounds containing a benzene fused to a pyrrolo[2,3-b]diazepine moiety. This specific chemical has the molecular formula C11H8N4 and is often used in the synthesis of various pharmaceutical and bioactive compounds. Additionally, it is used as a research tool in various chemical and biochemical studies, making it an important compound in both industrial and academic contexts.

Uses

Used in Pharmaceutical Synthesis:
1H-Pyrrolo[2,3-b]pyridine-3-acetonitrile is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of a wide range of bioactive molecules, making it a valuable asset in the development of new drugs.
Used in Chemical and Biochemical Research:
1H-Pyrrolo[2,3-b]pyridine-3-acetonitrile is used as a research tool in various chemical and biochemical studies. Its presence in experiments can help researchers understand the interactions and reactions of different molecules, contributing to the advancement of scientific knowledge in these fields.

InChI:InChI=1/C9H7N3/c10-4-3-7-6-12-9-8(7)2-1-5-11-9/h1-2,5-6H,3H2,(H,11,12)

Upstream product

• 5654-92-2 7-azagramine 
• 7677-24-9 trimethylsilyl cyanide 
• 87358-28-9 N,N,N-trimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)methanaminium iodide 
• 271-63-6 7-Azaindole 
• 50-00-0 formaldehyd 
• 773837-37-9 sodium cyanide 
• 77-78-1 dimethyl sulfate 
• 143-33-9 sodium cyanide 

Downstream Products

• 4649-12-1 2-(1H-pyrrolo[2,3-b]pyridin-3-yl)-ethylamine 
• 1912-42-1 (1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid 
• 1313530-14-1 2-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-oxo-3-(3,4,5-trimethoxyphenyl)propanenitrile 
• 1313529-93-9 5-amino-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazole 
• 1313530-15-2 5-amino-N-methyl-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazole-1-carbothioamide 
• 1313530-16-3 1-[5-amino-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazol-1-yl]ethanone 
• 1313530-17-4 2,2,2-trifluoro-N-(4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazol-5-yl)acetamide 
• 1313530-18-5 8-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-7-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a][1,3,5]triazine-2,4(1H,3H)-dione 
• 1313530-19-6 3-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-5,7-bis(trifluoromethyl)-2-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyrimidine 
• 5654-93-3 3-methyl-1H-pyrrolo<2,3-b>pyridine 
• 626605-11-6 4-{1-[3-(tert-butyl-diphenyl-silanyloxy)-propyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}-1'-triisopropylsilanyl-1'H-[3,3']bipyrrolyl-2,5-dione 
• 626605-16-1 3-{1-[3-(tert-butyldiphenylsilanyloxy)-propyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}-4-dibenzofuran-4-yl-pyrrole-2,5-dione 
• 626605-32-1 3-{1-[3-(tert-butyl-diphenyl-silanyloxy)-propyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}-4-(4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridin-2-yl)-pyrrole-2,5-dione 
• 626605-20-7 3-{1-[3-(tert-butyl-diphenyl-silanyloxy)-propyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}-4-quinolin-8-yl-pyrrole-2,5-dione 

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