441787-66-2 Usage
Structure
A derivative of propanone (acetone) with a 2-amino-1-[4-(2-methylpropoxy)phenyl]group attached
Usage
Commonly used in the production of pharmaceuticals and in research and development of new drugs
Medical potential
Has been studied for its potential use in treating certain medical conditions and has shown promise in preclinical studies
Importance in chemistry
Unique structure and properties make it a valuable component in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 441787-66-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,1,7,8 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 441787-66:
(8*4)+(7*4)+(6*1)+(5*7)+(4*8)+(3*7)+(2*6)+(1*6)=172
172 % 10 = 2
So 441787-66-2 is a valid CAS Registry Number.
441787-66-2Relevant academic research and scientific papers
Initial structure-activity relationship studies of a novel series of pyrrolo[1,2-a]pyrimid-7-ones as GnRH receptor antagonists
Zhu, Yun-Fei,Struthers,Connors, Jr., Patrick J.,Gao, Yinghong,Gross, Timothy D.,Saunders, John,Wilcoxen, Keith,Reinhart, Greg J.,Ling, Nicholas,Chen, Chen
, p. 399 - 402 (2007/10/03)
Initial SAR studies on 1-aminomethyl-2-aryl-3-cyano-pyrrolo[1,2-a]pyrimid-7-one-6-carboxylates as human GnRH receptor antagonists were discussed. 2-(2-Methylaminoethyl)pyridine was discovered to be a key feature for generating active compounds. The best compound from the series had 25 nM (Ki) binding affinity to human GnRH receptor.
