442159-37-7

Upstream product

• 497-03-0 2-methylbut-2-enal 
• 101711-78-8 (3R)-3-propionyl-4-benzyloxazolidin-2-one 

Downstream Products

• 442159-38-8 (R)-4-benzyl-3-((2R,3R,E)-3-(tert-butyldimethylsilyloxy)-2,4-dimethylhex-4-enoyl)oxazolidin-2-one 
• 442159-43-5 Benzoic acid (5E,9E)-(1S,3R,4S,7S,8R)-8-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-1,3,5,7,9-pentamethyl-2-oxo-undeca-5,9-dienyl ester 
• 442159-44-6 Benzoic acid (5E,9E)-(1S,3R,4S,7S,8R)-4,8-bis-(tert-butyl-dimethyl-silanyloxy)-1,3,5,7,9-pentamethyl-2-oxo-undeca-5,9-dienyl ester 
• 442159-50-4 (8E,12E)-(2S,6S,7S,10S,11R)-7,11-Bis-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-2,6,8,10,12-pentamethyl-3-oxo-tetradeca-8,12-dienoic acid benzyl ester 
• 442159-48-0 (4E,8E,12E)-(2S,6S,7S,10S,11R)-7,11-Bis-(tert-butyl-dimethyl-silanyloxy)-2,6,8,10,12-pentamethyl-3-oxo-2-trimethylsilanyloxy-tetradeca-4,8,12-trienoic acid benzyl ester 
• 442159-47-9 (8E,12E)-(2S,6S,7S,10S,11R)-7,11-Bis-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-2,6,8,10,12-pentamethyl-3-oxo-2-trimethylsilanyloxy-tetradeca-8,12-dienoic acid benzyl ester 
• 1610850-66-2 (S)-4-benzyl-3-((3S,4S,5R,E)-5-(tert-butyldimethylsilyloxy)-3-hydroxy-4,6-dimethyloct-6-enoyl)oxazolidin-2-one 
• 1610850-67-3 (S)-4-benzyl-3-((3R,4S,5R,E)-5-(tert-butyldimethylsilyloxy)-3-hydroxy-4,6-dimethyloct-6-enoyl)oxazolidin-2-one 
• 1610850-48-0 (2E,5S,6S,7R,8E)-((2S,3S)-1-(benzyloxy)-3-methyl-1-oxopentan-2-yl) 7-(tert-butyldimethylsilyloxy)-5-(methoxymethoxy)-2,6,8-trimethyldeca-2,8-dienoate 
• 1610850-78-6 C₅₄H₉₁N₅O₁₂Si 
• 1610850-88-8 C₆₀H₉₅N₅O₁₂Si 
• 1610850-82-2 C₄₈H₇₇N₅O₁₂ 
• 1610850-91-3 C₅₄H₈₁N₅O₁₂ 
• 1610850-92-4 C₄₇H₇₃N₅O₁₁ 

Relevant academic research and scientific papers

Synthetic studies on a cyclic hexadepsipeptide GE3: Stereoselective construction of the acyl side chain segment

Stereoselective synthesis of the acyl side chain segment 2 of GE3 (1), a potent inhibitor of cell progression of the cell cycle from the G1 to S phase, has been achieved by using Sharpless' asymmetric dihydroxylation and Evans' and Paterson's stereoselective aldol methodologies.

Toward the total synthesis of a lagunamide B analogue

Lagunamides, isolated from a marine cyanobacterium Lyngbya majuscule found in Singapore, showed very potent activities against Plasmodium falciparum and murine leukemia cell line (P388). Herein, a concise synthetic approach toward the total synthesis of a lagunamide B analogue is discussed. Macrolactonization, HWE-olefination, and modified Crimmin's aldol are some of the key reactions featured in this synthesis.