442199-08-8 Usage
Chemical structure
A piperidine ring with a carboxylic acid group, a pyrazine ring connected to the piperidine via an oxycarbonyl group, and a Boc protecting group (tert-butyloxycarbonyl) attached to the nitrogen atom of the pyrazine ring.
Molecular weight
280.32 g/mol
Appearance
Boc-pyrazine is a white crystalline solid.
Solubility
It is soluble in common organic solvents such as dichloromethane, ethyl acetate, and acetonitrile, but has low solubility in water.
Boc protecting group
The presence of the Boc group makes Boc-pyrazine a protected derivative of pyrazine, which helps prevent unwanted side reactions during organic synthesis.
Reactivity
Boc-pyrazine is known for its mild and selective reactivity, making it a valuable tool in the development of new chemical compounds.
Applications
Boc-pyrazine is widely utilized in the pharmaceutical industry for the production of various drugs and pharmaceutical intermediates. It is also used in the preparation of peptide and protein derivatives, which are important in the field of biochemistry and biotechnology.
Synthesis
Boc-pyrazine can be synthesized through various methods, including the reaction of pyrazine with Boc-protected intermediates or the use of other organic synthesis techniques.
Stability
Boc-pyrazine is generally stable under normal storage conditions, but it should be kept away from moisture and extreme temperatures to maintain its integrity.
Check Digit Verification of cas no
The CAS Registry Mumber 442199-08-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,2,1,9 and 9 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 442199-08:
(8*4)+(7*4)+(6*2)+(5*1)+(4*9)+(3*9)+(2*0)+(1*8)=148
148 % 10 = 8
So 442199-08-8 is a valid CAS Registry Number.
442199-08-8Relevant articles and documents
Peptide compounds
-
, (2008/06/13)
The present invention relates to a compound of the formula (I)wherein R1 is benzofuranyl substituted by halogen, or styryl substituted by halogen; R2 is substituted hydroxy, substituted mercapto or substituted sulfonyl; and X is or pharmaceutically acceptable salts thereof. The compound (1) of the present invention and pharmaceutically acceptable salts thereof possess a strong inhibitory activity on the production of nitric oxide (NO), and are useful for prevention and/or treatment of NO-mediated diseases in human being and animals.
