442202-23-5

Basic information

• Product Name: methyl (2S,3S,6S)-(-)-6-(tert-butyldiphenylsilyloxymethyl)-2-propenyl-3-vinylpiperidine-1-carboxylate
• Synonyms: methyl (2S,3S,6S)-(-)-6-(tert-butyldiphenylsilyloxymethyl)-2-propenyl-3-vinylpiperidine-1-carboxylate
• CAS NO: 442202-23-5
• Molecular Weight: 477.719
• Mol File: 442202-23-5.mol

Chemical Properties

• CAS DataBase Reference: methyl (2S,3S,6S)-(-)-6-(tert-butyldiphenylsilyloxymethyl)-2-propenyl-3-vinylpiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2S,3S,6S)-(-)-6-(tert-butyldiphenylsilyloxymethyl)-2-propenyl-3-vinylpiperidine-1-carboxylate(442202-23-5)
• EPA Substance Registry System: methyl (2S,3S,6S)-(-)-6-(tert-butyldiphenylsilyloxymethyl)-2-propenyl-3-vinylpiperidine-1-carboxylate(442202-23-5)

Safety Data

• Hazardous Substances Data: 442202-23-5(Hazardous Substances Data)

Upstream product

• 442202-05-3 dimethyl (S)-(-)-6-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydro-4H-pyridine-1,2-dicarboxylate 
• 442202-21-3 methyl (6S)-(-)-2-(tert-butyldiphenylsilyloxymethyl)-6-trifluoromethanesulfonyloxy-3,4-dihydro-2H-pyridine-1-carboxylate 
• 442202-22-4 dimethyl (2R,3S,6S)-(+)-6-(tert-butyldiphenylsilyloxymethyl)-3-vinyl-piperidine-1,2-dicarboxylate 
• 442202-06-4 methyl (2R,3S,6S)-(+)-6-(tert-butyldiphenylsilyloxymethyl)-2-hydroxymethyl-3-vinylpiperidine-1-carboxylate 
• 442202-20-2 methyl (6S)-(-)-2-(tert-butyldiphenylsilyloxymethyl)-6-oxopiperidine-1-carboxylate 
• 209257-75-0 (S)-6-((tert-butyldiphenylsilyloxy)methyl)piperidin-2-one 
• 1530-32-1 ethyltriphenylphosphonium bromide 

Downstream Products

• 442202-09-7 dimethyl (2S,3R,5R,6S)-(-)-5-ethyl-6-propyl-3-vinylpiperidine-1,2-dicarboxylate 

Relevant articles and documents

Stereodivergent synthesis of the 2,3,5,6-tetrasubstituted piperidine ring system: An application to the synthesis of alkaloids

Stereodivergent synthesis of the 2,3,5,6-tetrasubstituted piperidine ring system has been achieved by sequential stereocontrolled Michael-type conjugate addition reaction of appropriate enaminoesters. This methodology has been applied to the total synthes

Synthesis of alkaloid 223A and a structural revision.

[structure: see text] Synthesis of alkaloid 223A has been achieved by sequential use of our original conjugate addition reaction to enaminoesters as the key step. The proposed structure for natural 223A (A, absolute configuration unknown) was revised to B