4424-25-3

Usage

Uses

Used in Food Industry:
Benzoic acid, 5-methyl-2-(1-methylethyl)is used as a food preservative for its antimicrobial properties, effectively preventing the growth of mold, yeast, and bacteria in a variety of food products. This helps to extend the shelf life and maintain the quality of the products.
Used in Pharmaceutical Industry:
Benzoic acid, 5-methyl-2-(1-methylethyl)serves as a precursor in the synthesis of pharmaceuticals, contributing to the development of new drugs and improving the efficacy of existing medications.
Used in Chemical Industry:
Benzoic acid, 5-methyl-2-(1-methylethyl)is utilized in the production of various industrial chemicals, highlighting its versatility and importance in the chemical sector.
Used in Cosmetics and Personal Care Products:
It also functions as a fragrance or flavoring agent in cosmetics and personal care products, enhancing the sensory experience of these items while maintaining their quality and safety.

Upstream product

• 256637-50-0 2-isopropyl-5-methylphenyl trifluoromethanesulfonate 
• 124-38-9 carbon dioxide 

Downstream Products

• 1378950-19-6 4-methoxyphenyl 2-isopropyl-5-methylbenzoate 
• 1378950-26-5 N-(4-methoxyphenyl)-2-isopropyl-5-methylbenzamide 
• 1378950-22-1 N-(biphenyl-4-yl)-2-isopropyl-5-methylbenzamide 
• 1378950-00-5 4-tert-butylphenyl 2-isopropyl-5-methylbenzoate 
• 1378950-21-0 N-(4-trifluoromethylphenyl)-2-isopropyl-5-methylbenzamide 
• 861542-62-3 4-isopropylisophthalic acid 
• 854824-58-1 2-isopropyl-5-methyl-benzoic acid ethyl ester 

Relevant academic research and scientific papers

Carboxylation of Aryl Triflates with CO2 Merging Palladium and Visible-Light-Photoredox Catalysts

We report herein a visible-light-promoted, highly practical carboxylation of readily accessible aryl triflates at ambient temperature and a balloon pressure of CO2 by the combined use of palladium and photoredox Ir(III) catalysts. Strikingly, the stoichiometric metallic reductant is replaced by a nonmetallic amine reductant providing an environmentally benign carboxylation process. In addition, one-pot synthesis of a carboxylic acid directly from phenol and modification of estrone and concise synthesis of pharmaceutical drugs adapalene and bexarotene have been accomplished via late-stage carboxylation reaction. Furthermore, a parallel decarboxylation-carboxylation reaction has been demonstrated in an H-type closed vessel that is an interesting concept for the strategic sector. Spectroscopic and spectroelectrochemical studies indicated electron transfer from the Ir(III)/DIPEA combination to generate aryl carboxylate and Pd(0) for catalytic turnover.

Modulation of thermo-transient receptor potential (thermo-TRP) channels by thymol-based compounds

A series of thirty-three thymol, p-cymene-3-carboxylic acid, and 3-amino-p-cymene derivatives was synthesized and tested on TRPA1, TRPM8, and TRPV3 channels. Most of them acted as strong modulators of TRPA1, TRPM8, and TRPV3 channels with EC50 and/or IC50 values distinctly lower than those of thymol and related monoterpenoids. Some of the compounds examined, that is, 3c, 4e, f, 6b, and 8b exhibited an appreciable subtype-selectivity.

Palladium-catalyzed hydroxycarbonylation of aryl and vinyl triflates by in situ generated carbon monoxide under microwave irradiation

An operationally simple hydroxycarbonylation of aryl and vinyl inflates to the corresponding carboxylic acids with a palladium-mediated microwave system was carried out in water. Georg Thieme Verlag Stuttgart.