4425-95-0

Usage

Uses

Used in Polymer Production:
99FLUORENEDIPROPIONICACID is used as a stabilizer and antioxidant for enhancing the durability and performance of polymers. It helps to prevent the degradation of polymers caused by oxidation and heat, thereby extending their lifespan.
Used in Plastics Industry:
In the plastics industry, 99FLUORENEDIPROPIONICACID serves as a crucial additive, ensuring the stability and longevity of plastic products by protecting them from the effects of oxidation and heat.
Used in Rubber Industry:
99FLUORENEDIPROPIONICACID is utilized as a stabilizer in the rubber industry to improve the resistance of rubber materials against degradation, thus maintaining their elasticity and performance over time.
Used in Pharmaceutical Development:
99FLUORENEDIPROPIONICACID plays a significant role in the development of pharmaceuticals, where its antioxidant properties can be harnessed to enhance the stability and efficacy of various medicinal compounds.
Used as a Research Tool in Oxidation Studies:
As a research tool, 99FLUORENEDIPROPIONICACID aids scientists in studying oxidation processes, providing insights into the mechanisms of material degradation and the development of more effective protective measures.

Upstream product

• 4425-97-2 3-[9-(2-cyanoethyl)-9H-fluoren-9-yl]propionitrile 
• 86-73-7 9H-fluorene 
• 79-10-7 acrylic acid 

Relevant academic research and scientific papers

Synthesis and monoamine transporter binding properties of 2,3-cyclo analogues of 3β-(4′-aminophenyl)-2β-tropanemethanol

A series of cyclo-3β-(4-aminophenyl)-2β-tropanemethanol analogues (5a-m) possessing varying linker groups between the 2- and 3-position on the tropane ring were synthesized and evaluated for their monoamine transporter binding properties. The results show that binding to the dopamine and serotonin transporters (DAT and 5-HTT) is highly dependent on the specific linker used. Cyclo-3β-(4-aminophenyl)-2β-tropanemethanol pimelic acid ester/amide (5b) had an IC50 of 3.8 nM at the DAT. Cyclo-3β-(4-aminophenyl)- 2β-tropanemethanol sebacic acid ester/amide (5e) had a Ki of 1.9 nM at the 5-HTT and was 68- and 737-fold selective for the 5-HTT relative to the DAT and NET. Small changes to the size as well as the electrostatic and hydrophobic properties of the 2,3-linker in 5b or 5e led to much less potent analogues at all three transporters. These results suggest that the high affinity for 5b and 5e at the DAT and 5-HTT may be due to their specific conformational properties.

Preparation process of dicarboxylic acid compounds

Carboxylic acid compounds, each of which has an indene skeleton and represented by the following formula (2) or a fluorene skeleton and represented by the following formula (3), are each prepared by reacting an unsaturated carboxylic acid compound represented by the following formula (1) with indene or fluorene in the presence of a strong base catalyst: wherein R1, R2, R3 and R4 each independently represents an atom or group selected from a hydrogen atom, an alkyl group, an aryl group or a carboxyl group, with the proviso that at least one of R3 and R4 contains a carboxyl group or a salt thereof or a carboxylic ester group.