442513-39-5Relevant academic research and scientific papers
A convenient synthesis of 2-(alkylamino)pyridines
Krein, Douglas M.,Lowary, Todd L.
, p. 4965 - 4967 (2002)
The synthesis of a series of 2-(alkylamino) pyridines (1) in three steps from 2-aminopyridine (4) is reported. The products were obtained in 67-91% overal yield from 4.
Mesoionic pyrido[1,2-a]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide1
Zhang, Wenming,Holyoke, Caleb W.,Pahutski, Thomas F.,Lahm, George P.,Barry, James D.,Cordova, Daniel,Leighty, Robert M.,Singh, Vineet,Vicent, Daniel R.,Tong, My-Hanh T.,Hughes, Kenneth A.,McCann, Stephen F.,Henry, Yewande T.,Xu, Ming,Briddell, Twyla A.
, p. 16 - 20 (2016/12/14)
A novel class of mesoionic pyrido[1,2-a]pyrimidinones has been discovered with exceptional insecticidal activity controlling a number of insect species. In this communication, we report the part of the optimization program which led to the discovery of triflumezopyrim as a highly potent insecticide controlling various hopper species. Our efforts in discovery, synthesis, structure-activity relationship elucidation, and biological activity evaluation are also presented.
