442555-76-2Relevant academic research and scientific papers
Dansyl-styrylquinoline conjugate as divalent iron sensor
Praveen,Reddy,Luxmi Varma
, p. 6626 - 6629 (2010)
Synthesis and photophysical studies of a simple and efficient dansyl-styrylquinoline conjugate (DansSQ) which shows excellent selectivity towards Fe2+ over other transition metal ions including Fe 3+ is described. The fluorescent emi
Design, synthesis, and photochemistry of styrylquinoline -containing polymers
Kharchenko, Oksana,Smokal, Vitaliy,Krupka, Anastasia,Kolendo, Aleksiy
, p. 71 - 77 (2016)
Novel polymers with styrylquinoline moiety and different substituents units are presented. Styrylquinoline polymers were obtained by a three-step synthetic approach. This includes the condensation, preparation of a methacrylic monomers and their polymerization. Their photophysical and photochemical properties have been investigated. Polymers were characterized by 1HNMR, UV spectroscopy and GPC, DSC techniques. The synthesized polymers exhibited glass transition temperatures in the range of 153–184°C.
Supramolecular assembly of two two-folded helical structures based on 2-substituted 8-hydroxyquinoline complexes
Yuan, Guozan,Rong, Lulu,Yue, Caibo,Wei, Xianwen
, p. 19 - 24 (2013/07/27)
Based on two 2-substituted 8-hydroxyquinoline ligands containing NO 2 and Cl, two complexes [Co(L2)2(pyridine) 2] (1) and [Cu(L3)2] (2) were synthesized and characterized with single-crysta
Synthesis and antiproliferative evaluations of certain 2-phenylvinylquinoline (2-styrylquinoline) and 2-furanylvinylquinoline derivatives
Chang, Feng-Shuo,Chen, Weichung,Wang, Chihuei,Tzeng, Cherng-Chyi,Chen, Yeh-Long
experimental part, p. 124 - 133 (2010/04/06)
The present study describes the synthesis of 2-phenylvinylquinoline (styrylquinoline) and 2-furanylvinylquinoline derivatives and evaluation for their antiproliferative activities. (E)-2-Styrylquinolin-8-ol (14a) was inactive against a 3-cell line panel consisting of MCF-7 (Breast), NCI-H460 (Lung), and SF-268 (CNS). Replacement of the phenyl ring with 5-nitrofuran-2-yl group significantly enhanced antiproliferative activity in which (E)-2-(2-(5-nitrofuran-2-yl)vinyl)quinolin-8-ol (14i) and its 4-substituted derivatives 15-19 exhibited strong inhibitory effects against the growth of all three cancer cells. These compounds were further evaluated for their IC50 against the growth of MCF-7, LNCaP, and PC3. Results indicated that a hydrogen bond donating oxime derivative 19a was more active than its hydrogen bond accepting methyloxime derivative 19b. For the inhibition of LNCaP, the potency decreased in an order 14i > 19a > 19b > 15 > 18 > 16. Compound 14i is the most active with an IC50 value of 0.35 and 0.14 μM, respectively, against the growth of LNCaP and PC3 cancer cells. Therefore, compound 14i was evaluated by flow cytometric analysis for its effects on cell cycle distributions. Results indicated that 14i effectively induced cell cycle arrest at S phase for both cell lines, which consequently trigger late apoptosis for both LNCaP and PC3 cells.
