442669-65-0Relevant academic research and scientific papers
Reaction of α,β-alkynylketones with β-amino alcohols: Pseudoephedrine- assisted cleavage of triple bond via formal internal redox process
Vasilevsky, Sergei F.,Davydova, Maria P.,Mamatuyk, Victor I.,Pleshkova, Nadezhda V.,Fadeev, Dmitry S.,Alabugin, Igor V.
, p. 377 - 379 (2015/10/19)
Reaction of 3-aryl-1-(3,4,5-trimethoxyphenyl)prop-2-yn-1-ones with (+)-pseudoephedrine leads to products of alkyne moiety cleavage, namely, 1-(3,4,5-trimethoxyphenyl)ethanone and N-(1-hydroxy-1-phenylprop-2-yl)-N-methylbenzamides. In the course of the process one of alkyne carbons undergoes a formal reduction to a Me group, whereas the other one is oxidized to a C(O)NRR' moiety.
RUTHENIUM COMPOUND AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINOALCOHOL COMPOUND
-
Page/Page column 21, (2011/01/11)
A novel ruthenium compound that is useful as an asymmetric reduction catalyst for carbonyl compounds. The ruthenium compound of the present invention is represented by a formula (I): (Ru(X)2(Pxx)[R1R2C(NH2)-Rsu
Polymer-immobilized catalyst for asymmetric hydrogenation of racemic α-(N-benzoyl-N-methylamino)propiophenone
Chiwara, Vinia Ipai,Haraguchi, Naoki,Itsuno, Shinichi
experimental part, p. 1391 - 1393 (2009/07/04)
Asymmetric hydrogenation of α-(N-benzoyl-N-methylami-no)propiophenone through dynamic kinetic resolution was performed by using a polymer-immobilized chiral diamine-ruthenium-BINAP-t-BuOK system in order to yield syn-β-amidealcoholexclusivelywithnearlyperfectenantioselectivity.
