443283-24-7

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 1195779-19-1 C₃₀H₄₃NO₄SSi 
• 1438399-44-0 C₃₇H₆₁NO₄SSi₂ 
• 1438399-45-1 C₂₉H₄₈O₃Si₂ 

Downstream Products

• 245039-86-5 (3S,4S,5R,6S,7S)-6-(tert-Butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-3,5,7-trimethyl-oct-1-en-4-ol 
• 1438399-46-2 C₃₃H₅₃NO₄Si₂ 
• 245039-96-7 (3S,4R,7R,8S,9S,10R,11S,12S)-1-Benzyloxy-11-(tert-butyl-dimethyl-silanyloxy)-13-(tert-butyl-diphenyl-silanyloxy)-7-hydroxy-9-(4-methoxy-benzyloxymethoxy)-4,8,10,12-tetramethyl-3-triethylsilanyloxy-tridecan-5-one 
• 245039-93-4 (3S,4R,7R,8S,9S,10R,11S,12S)-1-[(benzyl)oxy]-11-[(tert-butyl-dimethylsilyl)oxy]-13-[(tert-butyl-diphenylsilyl)oxy]-7-hydroxy-9-[(methoxymethyl)oxy]-4,8,10,12-tetramethyl-3-[(triethylsilyl)oxy]-tridecan-5-one 
• 245039-91-2 (3S,4R,7R,8S,9S,10R,11S,12S)-1-[(benzyl)oxy]-11-[(tert-butyl-dimethylsilyl)oxy]-13-[(tert-butyl-diphenylsilyl)oxy]-7-hydroxy-3-methoxy-9-[(methoxymethyl)oxy]-4,8,10,12-tetramethyl-tridecan-5-one 
• 245039-83-2 (2R,3R,4R,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(tert-butyl-diphenyl-silanyloxy)-3-(4-methoxy-benzyloxymethoxy)-2,4,6-trimethyl-heptanal 
• 245039-90-1 (5R,6S,7S,8R,9S,10S)-9-[(tert-butyl-dimethylsilyl)oxy]-11-[(tert-butyl-diphenylsilyl)oxy]-5-hydroxy-7-[(methoxymethyl)oxy]-2,6,8,10-tetramethyl-undecan-3-one 
• 245039-87-6 (2R,3R,4R,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(tert-butyl-diphenyl-silanyloxy)-3-methoxymethoxy-2,4,6-trimethyl-heptanal 

Relevant academic research and scientific papers

Highly stereoselective syntheses of (E)-δ-boryl-anti-homoallylic alcoholsviaallylation with α-boryl-(E)-crotylboronate

A highly stereoselective synthesis of (E)-δ-boryl-anti-homoallylic alcohols is developed. In the presence of a Lewis acid, aldehyde allylation with α-boryl-(E)-crotylboronate gave δ-boryl-anti-homoallylic alcohols in good yields with excellentE-selectivity. TheE-vinylboronate group in the products provides a useful handle for cross-coupling reactions as illustrated in the fragment synthesis of chaxamycins.

A highly stereoselective synthesis of glycidic amides based on a new class of chiral sulfonium salts: Applications in asymmetric synthesis

A new type of chiral sulfonium salts that are characterized by a bicyclic system has been designed and synthesized from α-amino acids. Their corresponding ylides, which were prepared by basic treatment of the sulfonium salts, reacted smoothly with a broad array of simple and chiral aldehydes to provide trans-epoxy amides in reasonable to very good yields and excellent stereoselectivities (>98 %). The obtained epoxy amides were found to be useful as synthetic building blocks. Thus, they were reduced into their corresponding epoxy alcohols and subjected to oxirane-ring-opening reactions with different types of nucleophiles.

Studies of fragment assembly aldol reactions of chiral aldehydes and chiral methyl ketones: Stereoselective synthesis of the C(13)-C(25) segment of scytophycin C

A highly stereoselective synthesis of the C(13)-C(25) fragment of scytophycin C is described, along with stereochemical studies of the key fragment assembly methyl ketone aldol reaction.