443296-39-7Relevant academic research and scientific papers
Synthesis of novel chiral Schiff bases and their application in asymmetric transfer hydrogenation of prochiral ketones
Zhou, Zhongqiang,Bian, Yongjun
experimental part, p. 682 - 687 (2010/11/04)
Novel chiral Schiff bases were synthesized from (+)-camphor, and their application to asymmetric transfer hydrogenation of prochiral ketones is described. The asymmetric transfer hydrogenation reaction could afford excellent conversion rates (up to 97.3%) and up to 27.3% enantiomeric excess.
A novel approach for the synthesis of alkyl and aryl sulfonamides
Shaabani, Ahmad,Soleimani, Ebrahim,Hossein Rezayan, Ali
, p. 2185 - 2188 (2008/02/04)
A novel approach for the synthesis of alkyl and aryl sulfonamides by the reaction of sulfonic acids, isocyanides and water in dichloromethane is reported at ambient temperature in excellent yields within 20 min. To the best of our knowledge this is the first report on the synthesis of this biologically important family using easily available sulfonic acids and isocyanides.
Trans-1-sulfonylamino-2-isoborneolsulfonylaminocyclohexane derivatives: Excellent chiral ligands for the catalytic enantioselective addition of organozinc reagents to ketones
Forrat, Vicente J.,Prieto, Oscar,Ramon, Diego J.,Yus, Miguel
, p. 4431 - 4445 (2008/02/08)
The catalytic enantioselective addition of different organozinc reagents (such as alkyl and aryl derivatives or in situ generated aryl, allyl alkenyl, and alkynyl derivatives obtained through different transmetallation processes) to simple ketones has bee
Enantioselective synthesis of α-amino acids from glycine t-butyl ester
Yeh, Tsai-Lung,Liao, Chun-Chen,Uang, Biing-Jiun
, p. 11141 - 11152 (2007/10/03)
Enantioselective syntheses of optically active α-amino acids from glycine t-butyl ester through Schiff base employing (+)-N-alkyl-10-camphorsulfonamides as chiral auxiliaries were described. Methylation of Schiff base 5 gave high asymmetric inductions, whereas ethylation, allylation and benzylation gave fair asymmetric inductions. The stereochemistry of the major alkylation product was S configuration at the newly formed stereogenic center with the exception of the benzylation reaction in which the R configuration was generated.
