443303-95-5

Upstream product

• 313963-43-8 (12R,15S,16R/S,19R,20S,34R,35R)-34,35-dimethoxy-34,35-dimethyl-19-(12-(9-benzyloxypropyl)-15-(16-hydroxyprop-17-ynyl)tetrahydrofuran)-20-dodecanyl-[33,36]-dioxane 
• 243964-15-0 (-)-(2S,3R,5R,6R)-3-tert-butyldimethylsilyloxymethyl-2-hydroxymethyl-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane 
• 243964-22-9 (2R,3R,5R,6R)-3-[[tert-butyl(dimethyl)silyl]oxymethyl]-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2-carbaldehyde 
• 243964-13-8 [(2R,3S,5R,6R)-3-(hydroxymethyl)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl]methanol 
• 201472-26-6 (2R/S,5S)-5-(tert-butyldiphenylsilyloxymethyl)tetrahydrofuran-2-ol 
• 100-39-0 benzyl bromide 
• 313963-51-8 (12R,15S,16R/S,19R,20S,34R,35R)-34,35-dimethoxy-34,35-dimethyl-19-(12-(9-benzyloxypropyl)-15-(16-hydroxypropyl)tetrahydrofuran)-20-dodecanyl-[33,36]-dioxane 
• 313963-27-8 (2S,3R,5R,6R)-3-tert-butyldimethylsilyloxymethyl-5,6-dimethoxy-5,6-dimethyl-2-dodecane-[1,4]-dioxane 
• 313963-47-2 tert-Butyl-[(2R,3S,5R,6R)-3-((E)-dodec-1-enyl)-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxan-2-ylmethoxy]-dimethyl-silane 
• 313963-33-6 (2S,5S)-2-(tert-butyldiphenylsilyloxymethyl)-5-(1-benzyloxyprop-2-ynyl)tetrahydrofuran 
• 313963-28-9 (2S,3R,5R,6R)-5,6-dimethoxy-5,6-dimethyl-2-dodecane-3-(2',2'-gem-dibromo)ethenyl-[1,4]-dioxane 
• 313963-48-3 (2S,3R,5R,6R)-5,6-dimethoxy-5,6-dimethyl-3-hydroxymethyl-2-dodecane-[1,4]-dioxane 
• 443303-99-9 (2S,3S,5R,6R)-3-Dodecyl-5,6-dimethoxy-5,6-dimethyl-[1,4]dioxane-2-carbaldehyde 
• 313963-30-3 (2R/S,5S)-5-(tert-butyldiphenylsilyloxymethyl)-2-(prop-2-yne-1-oxy)tetrahydrofuran 

Downstream Products

• 313963-44-9 (12R,15S,16S,19R,20S,34R,35R)-34,35-dimethoxy-34,35-dimethyl-19-(12-(9-benzyloxypropyl)-15-(16-hydroxypropyl)tetrahydrofuran)-20-dodecanyl-[33,36]-dioxane 
• 443303-96-6 (12R,15S,16S,19R,20S,34R,35R)-34,35-dimethoxy-34,35-dimethyl-19-(12-(9-benzyloxypropyl)-15-(16-tert-butyldimethylsilyloxypropyl)tetrahydrofuran)-20-dodecanyl-[33,36]-dioxane 

Relevant academic research and scientific papers

The total synthesis of the annonaceous acetogenin, muricatetrocin C

The total synthesis of the potential antitumour agent muricatetrocin C has provided an ideal stage for the exploitation and development of new chemistry. A convergent synthetic strategy has been realised incorporating three distinct pieces of methodology, these include a highly diastereoselective hetero-Diels -Alder reaction to construct the butenolide terminus, an oxygen to carbon rearrangement to install the trans-2,5-disubstituted tetrahydrofuran ring and a spatial desymmetrisation process to afford the anti-diol unit.