4434-66-6Relevant academic research and scientific papers
The synthesis of single enantiomers of a meromycolic acid
Al Dulayymi,Baird,Roberts
, p. 7107 - 7110 (2000)
3-Oxa-2,4-dioxobicyclo[3.1.0]hexane provides a flexible starting material for the preparation of single enantiomers of a meromycolic acid, a long chain fatty acid containing two remote cis-cyclopropanes. (C) 2000 Elsevier Science Ltd.
Microwave and ultrasound assisted first synthesis of 12-hydroxyhentriacontane
Kaur, Jasamrit,Kaur, Irvinder,Jindal, Gitanjali,Manhas, Priya,Gupta, Neeru,Singh, Jasvinder
, p. 230 - 232 (2015)
An aliphatic alcohol 12-hydroxyhentriacontane has been synthesised for the first time. The synthetic route of this naturally occurring alcohol adopts the techniques of microwave and ultrasonic irradiation. The synthetic approach provided enough material to corroborate the structure of the target molecule which had been isolated from leaves of Ziziphus mauritiana and exhibits excellent anti-inflammatory, antibacterial and antimicrobial properties.
The synthesis of a single enantiomer of a major α-mycolic acid of M. tuberculosis
Al Dulayymi, Juma'a R.,Baird, Mark S.,Roberts, Evan
, p. 11939 - 11951 (2007/10/03)
We report a synthesis of a single enantiomer of a mycolic acid from Mycobacterium tuberculosis containing a di-cis-cyclopropane. The method can be simply varied to modify the chain lengths or the absolute stereochemistry of either cyclopropane.
Anti-mycobacterial compositions and their use for the treatment of tuberculosis and related diseases
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, (2008/06/13)
Compounds, pharmaceutical compositions, and methods for the treatment of mycobacterial diseases, such as tuberculosis and leprosy, are provided. Use of the compounds for promoting an antiseptic condition of a surface are also included. Some of the preferred compounds include thiatetracosanoic acids, esters, and fluorinated analogs.
UNSATURATED ANALOGUES OF 1-TRIACONTANOL
Kocian, Oldrich,Stransky, Karel,Zavada, Jiri
, p. 1346 - 1355 (2007/10/02)
A simple regio- and stereoselective synthesis of unsaturated analogues of the plant growth stimulator 1-triacontanol from ω-alkyn-1-ols is reported.Starting from the easily accessible 10-undecyn-1-ol, eight n-C30 alcohols containing , (E) -C=C- or (Z) -C=C- group in the position 21 and/or 10 have been prepared.Spectral and gas-chromatographic properties (Kovats retention indices) of the novel compounds are described.
