4436-23-1Relevant articles and documents
Rhodium-Catalyzed Regioselective Formal Hydroacylation of Vinyl Epoxides toward Esters Involving β-Carbon Cleavage
Chang, Zhi-Xin,Gong, Fei-Yuan,Wang, Xiaodan,Zhang, Tongbo,Han, Junfen,Li, Hong-Shuang
supporting information, p. 6084 - 6089 (2021/08/16)
Herein we disclose the first example of the formal hydroacylation reactions of vinyl epoxides with chelating aldehydes enabled by rhodium catalysis for the efficient construction of functionalized esters. Detailed investigations of the mechanistic pathway reveal that the presence of a 2-vinyl group is essential in contributing to the success of this regioselective reaction, which might proceed through β-carbon cleavage as the key procedure.
Palladium-catalyzed hiyama cross-couplings of arylsilanes with 3-Iodoazetidine: Synthesis of 3-arylazetidines
Liu, Zhenwei,Luan, Nannan,Shen, Linhua,Li, Jingya,Zou, Dapeng,Wu, Yusheng,Wu, Yangjie
, p. 12358 - 12365 (2019/10/11)
The first palladium-catalyzed Hiyama cross-coupling reactions of arylsilanes with 3-iodoazetidine were described. The protocol provides a convenient access to a variety of useful 3-arylazetidines which are of great interest in pharmaceutical laboratories in moderate to good yields (30%-88%). In addition, this strategy has the advantage of easy operation and mild reaction conditions.
2-Lithiated-2-phenyloxetane: A new attractive synthon for the preparation of oxetane derivatives
Coppi, Donato Ivan,Salomone, Antonio,Perna, Filippo Maria,Capriati, Vito
scheme or table, p. 9918 - 9920 (2011/10/09)
A valuable and direct method to access 2-substituted-2-phenyloxetanes by electrophilic quenching of the corresponding 2-lithiated derivative has, for the first time, been described. 2-Lithiated-2-phenyloxetane was found to be configurationally unstable. E
