443687-93-2 Usage
Uses
Used in Pharmaceutical Industry:
MEMA is utilized as a key intermediate in the synthesis of pharmaceuticals, leveraging its reactivity to form heterocyclic compounds that possess specific biological activities. Its potential applications in this field are vast, given the diversity of compounds that can be synthesized from this versatile building block.
Used in Agrochemical Industry:
In agrochemicals, MEMA serves as a crucial component in the development of new compounds designed to address various agricultural needs, such as pest control and crop protection. Its unique structure and reactivity contribute to the creation of novel agrochemicals with improved efficacy and selectivity.
Used in Material Science:
MEMA is employed as a building block in material science for the synthesis of advanced materials with tailored properties. Its incorporation into polymers, for instance, can lead to materials with enhanced mechanical, thermal, or electrical characteristics, depending on the specific application requirements.
Used in Catalysis and Organic Transformations:
MEMA has demonstrated promise in the development of new catalytic processes, where it can act as a catalyst or a catalyst support, facilitating various organic reactions. Additionally, it is used as a reagent in organic transformations, enabling the synthesis of complex molecules through its unique reactivity with other chemical entities.
Overall, the diverse applications of (8-Phenyl-1,4-dioxaspiro[4.5]dec-8-yl)MethanaMine, or MEMA, underscore its importance in various scientific and industrial fields, making it a valuable asset in the development of innovative products and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 443687-93-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,3,6,8 and 7 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 443687-93:
(8*4)+(7*4)+(6*3)+(5*6)+(4*8)+(3*7)+(2*9)+(1*3)=182
182 % 10 = 2
So 443687-93-2 is a valid CAS Registry Number.
443687-93-2Relevant academic research and scientific papers
Pseudosaccharin amines as potent and selective KV1.5 blockers
Lloyd, John,Finlay, Heather J.,Kover, Alexander,Johnson, James,Pi, Zulan,Jiang, Ji,Neels, James,Cavallaro, Cullen,Wexler, Ruth,Conder, Mary Lee,Shi, Hong,Li, Danshi,Sun, Huabin,Chimalakonda, Anjaneya,Huang, Christine,Salvati, Mark,Levesque, Paul
, p. 4983 - 4986 (2015/03/30)
Phenethyl aminoheterocycles like compound 1 were known to be potent IKur blockers although they lacked potency in vivo. Modification of the heterocycle led to the design and synthesis of pseudosaccharin amines. Compounds such as 14, 17d and 21c were found to be potent KV1.5 blockers and selective over other cardiac ion channels. These compounds had potent pharmacodynamic activity, however, they also showed off-target activities such as hemodynamic effects.
SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES
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Page/Page column 34, (2009/10/06)
The invention relates to compounds that have an affinity to the μ-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
Fused heterocyclic compounds
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Page/Page column 18, (2010/02/14)
A compound of formula I wherein m, n, A, B, D, E, G, H, Y, R1, R2, R3, R4, R5, and R8, are described herein.
Carbocyclic potassium channel inhibitors
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, (2008/06/13)
The present invention relates to a class of carbocyclic compounds of Formula I that are useful as potassium channel inhibitors to treat autoimmune disorders, cardiac arrhythmias, and the like.
Benzamide potassium channel inhibitors
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, (2008/06/13)
This invention relates to benzamide potassium channel inhibitors of general structural Formula I. The compounds of this invention are useful in the treatment of autoimmune diseases, the prevention of rejection of foreign organ transplants and related affl
