51509-98-9

Basic information

• Product Name: 4-Cyano-4-phenylcyclohexanone ethylene ketal
• Synonyms: 4-Cyano-4-phenylcyclohexanone ethylene ketal
• CAS NO: 51509-98-9
• Molecular Formula: C₁₅H₁₇NO₂
• Molecular Weight: 243.30098
• Mol File: 51509-98-9.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Cyano-4-phenylcyclohexanone ethylene ketal(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Cyano-4-phenylcyclohexanone ethylene ketal(51509-98-9)
• EPA Substance Registry System: 4-Cyano-4-phenylcyclohexanone ethylene ketal(51509-98-9)

Safety Data

• Hazardous Substances Data: 51509-98-9(Hazardous Substances Data)

Usage

General Description

4-Cyano-4-phenylcyclohexanone ethylene ketal is a chemical compound with the molecular formula C17H17NO2. It is a ketal derivative of 4-cyano-4-phenylcyclohexanone, which is used as an intermediate in organic synthesis. 4-Cyano-4-phenylcyclohexanone ethylene ketal has potential uses in pharmaceuticals and agrochemicals due to its ability to modify the properties of other organic molecules. It is also used in research and development as a building block for the synthesis of more complex chemical compounds. However, the specific properties and applications of 4-Cyano-4-phenylcyclohexanone ethylene ketal are still being investigated and studied.

Upstream product

• 25115-74-6 4-cyano-4-phenylcyclohexanone 
• 140-29-4 phenylacetonitrile 
• 75945-89-0 2.2-Bis-β-chlorethyl-1.3-dioxolan 
• 107-21-1 ethylene glycol 
• 38289-20-2 methyl 5-cyano-5-phenyl-2-oxocyclohexanecarboxylate 
• 3592-25-4 1,5-dichloropentan-3-one 

Downstream Products

• 25163-93-3 8-phenyl-1,4-dioxaspiro[4,5]decane 
• 443687-93-2 4-aminomethyl-4-phenylcyclohexanone ethyleneglycol ketal 
• 4894-75-1 1-phenyl-4-cyclohexanone 
• 75945-90-3 4-Oxo-1-phenyl-cyclohexancarbonsaeuremethylester 
• 75945-91-4 4-oxo-1-phenylcyclohexanecarboxylic acid 
• 51510-00-0 (8-phenyl-1,4-dioxaspiro[4.5]decan-8-yl)methanol 
• 57027-82-4 4-acetyl-4-phenylcyclohexanone 
• 25115-74-6 4-cyano-4-phenylcyclohexanone 
• 51509-99-0 8-Phenyl-1,4-dioxaspiro<4.5>decan-8-carbonsaeure 
• 56327-24-3 8-phenyl-1,4-dioxaspiro[4,5]decane-8-carboxaldehyde 

Relevant articles and documents

Pseudosaccharin amines as potent and selective KV1.5 blockers

Phenethyl aminoheterocycles like compound 1 were known to be potent IKur blockers although they lacked potency in vivo. Modification of the heterocycle led to the design and synthesis of pseudosaccharin amines. Compounds such as 14, 17d and 21c were found to be potent KV1.5 blockers and selective over other cardiac ion channels. These compounds had potent pharmacodynamic activity, however, they also showed off-target activities such as hemodynamic effects.

Synthesis and optimization of novel 4,4-disubstituted cyclohexylbenzamide derivatives as potent 11β-HSD1 inhibitors

The synthesis and SAR of a series of 4,4-disubstituted cyclohexylbenzamide inhibitors of 11β-HSD1 are described. Optimization rapidly led to potent, highly selective, and orally bioavailable inhibitors demonstrating efficacy in both rat and non-human primate ex vivo pharmacodynamic models.

Spirocyclic Azaindole Derivatives

The invention relates to substituted azaindole derivatives, to methods for the production thereof, to medicaments containing said compounds and to the use of substituted azaindole derivatives for producing medicaments.