4437-24-5Relevant academic research and scientific papers
Palladium-Catalyzed Decarboxylative Benzylation of Acetylides and Enolates
Torregrosa, Robert R. P.,Mendis, Shehani N.,Davies, Alex,Tunge, Jon A.
, p. 3205 - 3216 (2018/08/17)
Benzylic alkylation of enolates and acetylides has been achieved through the use of a decarboxylative benzylation strategy. Previous research in this area is often limited by the need for extended conjugation in the electrophiles that are coupled. Herein, we report that the use of 1,1'-bis(diphenylphosphino)ferrocene (dppf) ligand allows the coupling of simple benzyl electrophiles with enolates, while the use of XPhos ligand promotes the decarboxylative couplings of propiolates.
Lewis acid catalyzed propargylation of arenes with O-propargyl trichloroacetimidates: Synthesis of 1,3-diarylpropynes
Li, Changkun,Wang, Jianbo
, p. 7431 - 7434 (2008/02/11)
(Chemical Equation Presented) The BF3·OEt 2-catalyzed Friedel-Crafts propargylation of aromatic compounds with O-propargyl trichloroacetimidates is highly efficient and affords 1,3-diarylpropyne derivatives in good yields.
