443729-67-7

Basic information

• Product Name: Ethanone, 1-(4-iodo-1H-pyrrolo[2,3-b]pyridin-1-yl)-
• Synonyms: Ethanone, 1-(4-iodo-1H-pyrrolo[2,3-b]pyridin-1-yl)-;4-Iodo-1-acetyl-7-azaindole
• CAS NO: 443729-67-7
• Molecular Formula: C₉H₇IN₂O
• Molecular Weight: 286.06915
• Mol File: 443729-67-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Ethanone, 1-(4-iodo-1H-pyrrolo[2,3-b]pyridin-1-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-iodo-1H-pyrrolo[2,3-b]pyridin-1-yl)-(443729-67-7)
• EPA Substance Registry System: Ethanone, 1-(4-iodo-1H-pyrrolo[2,3-b]pyridin-1-yl)-(443729-67-7)

Safety Data

• Hazardous Substances Data: 443729-67-7(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(4-iodo-1H-pyrrolo[2,3-b]pyridin-1-yl)- is a chemical compound that belongs to the class of ethanones. Its molecular structure includes a pyrrolopyridine ring with an attached iodine atom. Ethanone, 1-(4-iodo-1H-pyrrolo[2,3-b]pyridin-1-yl)- may have potential applications in the fields of medicinal chemistry and drug discovery due to its unique structure and potential biological activity. Additionally, it may be used as a building block for the synthesis of other complex organic compounds. Further research and investigation are needed to fully understand the properties and potential uses of this chemical.

Upstream product

• 75-36-5 acetyl chloride 
• 55052-28-3 4-chloro-7-azaindole 

Downstream Products

• 618446-36-9 1-acetyl-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile 
• 940949-57-5 1-[2-deoxy-3,5-di-O-(toluoyl)-β-D-ribofuranosyl]-4-iodo-pyrrolo[2,3-b]pyridine 
• 1287240-29-2 1-[2-deoxy-3,5-di-O-(toluoyl)-β-D-ribofuranosyl]-4-[2,2'-bithien-5-yl]-pyrrolo[2,3-b]pyridine 
• 351439-07-1 methyl 1H-pyrrolo[2,3-b]pyridine-4-carboxylate 

Relevant articles and documents

NOVEL ARTIFICIAL FLUORESCENT BASES

The present invention relates to novel unnatural fluorescent nucleic acid bases, that is, a purine base, a 2-deazapurine base, and a 2,7-deazapurine base each having a functional group which consists of two or more heterocyclic moieties linked together, at the 6-position thereof (the 6-position of purine ring). The present invention also relates to a compound containing the unnatural base, a derivative thereof, and a nucleic acid containing a nucleotide having the unnatural base. The present invention also relates to a method of preparing the nucleic acid. The unnatural base of the present invention has excellent fluorescence characteristics and also has excellent properties as a universal base.

SUBSTITUTED ARYL-AMINE DERIVATIVES AND METHODS OF USE

The present invention provides classes of compounds, including-their pharmaceutically acceptable derivatives, useful for treating angiogenesis and related diseases such as cancer. Formula I and II wherein R is a 9- or 10-membered heterocyclyl ring selected from 7-isoquinolinyl,..2-methyl-3-oxo-2,3-dihydroindazol-6-yl, [1,6]-naphthydrin-3-yl, [1,7]-naphthydrin-2-yl, 1-oxo-2,3-dihydrobenzofuran-4-yl, 3-oxo-2,3-dihydrobenzofuran-5-yl, dihydro-benzodioxinyl, 6-quinazolinyl, 2-amino-6-quinazolinyl, 4-methylamino-6-quinazolinyl, 2,4-diamino-6 quinazolinyl, 3-oxo-3,4-dihydro-1,4-benzoxazin-6-yl, 2,2-difluoro-l;3-benzodioxol-5-yl and 2,2,3,3 tetrafluoro-2,3-dihydro-l,4-benzodioxin-6-yl, each of which is optionally substituted with one or more substituents selected from halo, haloakyl, C1-6 alkyl, C2-8 alkenyl, C2-8 alkynyl, N-dimethylamino-C1-6-alkyl, N-dimethylamino-C1-6-alkoxy, amino, alkyl-carbonylamino, morpholino-sulfonyl, amino-sulfonyl, oxazolyl, pyrrolyl,4 morpholinyl, carboxyl, cyano, and acetyl; wherein R1 in formula I is selected from unsubstituted or substituted phenyl, 5-6 membered heteroaryl, 9-10 membered bicyclic heterocyclyl and 11-14 membered tricyclic heterocyclyl, and R1 in formula II is selected from specific bicyclic heterocycles.

Substituted alkylamine derivatives and methods of use

Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.