443770-53-4Relevant academic research and scientific papers
Total synthesis of pyridovericin: studies toward the biomimetic synthesis of pyridomacrolidin.
Baldwin, Jack E,Adlington, Robert M,Conte, Aurelia,Irlapati, Nageswara Rao,Marquez, Rodolfo,Pritchard, Gareth J
, p. 2125 - 2127 (2002)
[reaction: see text] The total synthesis of the novel metabolite pyridovericin 1 is reported. The synthesis of this key intermediate in our proposed biomimetic synthesis of pyridomacrolidin 2 has been accomplished in good yield from readily available 2,4-dihydroxypyridine.
Total synthesis of pyridovericin
Irlapati, Nageswara Rao,Adlington, Robert M.,Conte, Aurelia,Pritchard, Gareth J.,Marquez, Rodolfo,Baldwin, Jack E.
, p. 9307 - 9317 (2007/10/03)
The total synthesis of the naturally occurring kinase inhibitor pyridovericin 1 is reported. A flexible and efficient synthesis has been accomplished in good yield from readily available 2,4-dihydroxypyridine. Pyridovericin is a key intermediate in our pr
