443791-02-4Relevant academic research and scientific papers
Highly Selective Synthesis of a 2-Deoxyxylonolactam via Enantioselective Carbon-Hydrogen Insertion Reactions Using Chiral Dirhodium(II) Carboxamidates
Doyle, Michael P.,Yan, Ming,Phillips, Iain M.,Timmons, Daren J.
, p. 91 - 95 (2007/10/03)
N-Benzyl-2-deoxyxylonolactams are accessible by highly chemoselective, diastereoselective, and enantioselective carbon-hydrogen insertion reactions of diazoacetamides. Competing aromatic cycloaddition or β-lactam formation via carbon-hydrogen insertion into a benzylic position can be minimized by the proper selection of chiral catalyst. Conformational influences are important in product preference.
