4439-70-7Relevant academic research and scientific papers
Synthesis of benzofuran scaffold-based potential PTP-1B inhibitors
Dixit, Manish,Tripathi, Brajendra K.,Tamrakar, Akhilesh K.,Srivastava, Arvind K.,Kumar, Brijesh,Goel, Atul
, p. 727 - 734 (2007/10/03)
Protein tyrosine phosphatase 1B (PTP-1B) is an enzyme that plays a critical role in down-regulating insulin signaling through dephosphorylation of the insulin receptor. Studies have shown that PTP-1B knockout mice showed increased insulin sensitivity in m
