443924-76-3

Basic information

• Product Name: (S)-3-[5-(2,5-Dimethyl-phenoxy)-pentanoyl]-4-isopropyl-oxazolidin-2-one
• Synonyms: (S)-3-[5-(2,5-Dimethyl-phenoxy)-pentanoyl]-4-isopropyl-oxazolidin-2-one
• CAS NO: 443924-76-3
• Molecular Weight: 333.428
• Mol File: 443924-76-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-[5-(2,5-Dimethyl-phenoxy)-pentanoyl]-4-isopropyl-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-[5-(2,5-Dimethyl-phenoxy)-pentanoyl]-4-isopropyl-oxazolidin-2-one(443924-76-3)
• EPA Substance Registry System: (S)-3-[5-(2,5-Dimethyl-phenoxy)-pentanoyl]-4-isopropyl-oxazolidin-2-one(443924-76-3)

Safety Data

• Hazardous Substances Data: 443924-76-3(Hazardous Substances Data)

Upstream product

• 443924-70-7 ethyl 5-(2,5-dimethylphenoxy)pentanoate 
• 443924-74-1 5-(2,5-dimethylphenoxy)pentanoic acid 
• 38585-38-5 sodium 2,5-dimethylphenolate 
• 14660-52-7 ethyl 5-bromovalerate 
• 17016-83-0 (4S)-4-isopropyl-1,3-oxazolidin-2-one 
• 443924-75-2 5-(2,5-dimethyl-phenoxy)-pentanoyl chloride 

Relevant articles and documents

Synthesis and antiplatelet activity of gemfibrozil chiral analogues

The chiral analogues of gemfibrozil 5-(2,5-dimethylphenoxy)-2-methylpentanoic acid and 5-(2,5-dimethylphenoxy)-2-ethylpentanoic acid were synthesized in optically active form using (S)-4-(1-methylethyl)-2-oxazolidinone as chiral auxiliary. All compounds inhibit human platelet aggregation. From these data, one can surmise that all tested compounds and gemfibrozil act at the platelet level with different mechanism than that of ASA, even if with a different potency.