443956-08-9

Basic information

• Product Name: 6-Bromo-2-nitro-pyridin-3-ol
• Synonyms: 6-Bromo-2-nitro-pyridin-3-ol;6-Bromo-3-hydroxy-2-nitropyridine;2-Bromo-5-hydroxy-6-nitropyridine;2-nitro-3-hydroxy-6-broMopyridine;2-broMo-6-nitropyridin-3-ol;2- bromine -5- hydroxyl -6- nitropyridine
• CAS NO: 443956-08-9
• Molecular Formula: C₅H₃BrN₂O₃
• Molecular Weight: 219
• Mol File: 443956-08-9.mol
• Article Data: 37

Chemical Properties

• Boiling Point: 412.975 °C at 760 mmHg
• Flash Point: 203.56 °C
• Appearance: /
• Density: 2.007 g/cm³
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -1.31±0.10(Predicted)
• CAS DataBase Reference: 6-Bromo-2-nitro-pyridin-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromo-2-nitro-pyridin-3-ol(443956-08-9)
• EPA Substance Registry System: 6-Bromo-2-nitro-pyridin-3-ol(443956-08-9)

Safety Data

• Hazardous Substances Data: 443956-08-9(Hazardous Substances Data)

Usage

Uses

6-?Bromo-?2-?nitropyridin-?3-?ol acts as a reagent for the synthesis of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad spectrum antibacterial agents. Also, functions as a reagent for the preparation of α-styrylpyridines via palladium-catalyzed coupling of N-tosylhydrazones with halopyridines, and their antitumor activity.

InChI:InChI=1S/C5H3BrN2O3/c6-4-2-1-3(9)5(7-4)8(10)11/h1-2,9H

Upstream product

• 916737-76-3 6-bromo-3-methoxy-2-nitropyridine 
• 15128-82-2 3-hydroxy-2-nitropyridine 

Relevant articles and documents

ANTI-BACTERIAL HETEROCYCLIC COMPOUNDS AND THEIR SYNTHESIS

The compounds of Formula I and Formula (B) are described herein along with their stereoisomers, pharmaceutically acceptable salts, complexes, hydrates, solvates, tautomers, polymorphs, racemic mixtures, optically active forms, and pharmaceutically active

COMPOUNDS AND THEIR METHODS OF USE

The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including Dravet syndrome or epilepsy are also provided herein.

FORMULATIONS FOR 2-HETEROARYL SUBSTITUTED BENZOFURANS

Processes and compositions for 2-heteroaryl substituted benzofuran derivatives are described. The 2-heteroaryl substituted benzofuran derivatives may be suitable for preparing radiolabeled 2-heteroaryl substituted benzofuran derivatives for imaging amyloid deposits in living patients.