443991-10-4

Basic information

• Product Name: Pentanenitrile, 3-ethyl-2-[[(1S)-1-phenylethyl]amino]-, (2S)-
• CAS NO: 443991-10-4
• Molecular Formula: C15H22N2
• Molecular Weight: 230.353
• Mol File: 443991-10-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Pentanenitrile, 3-ethyl-2-[[(1S)-1-phenylethyl]amino]-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanenitrile, 3-ethyl-2-[[(1S)-1-phenylethyl]amino]-, (2S)-(443991-10-4)
• EPA Substance Registry System: Pentanenitrile, 3-ethyl-2-[[(1S)-1-phenylethyl]amino]-, (2S)-(443991-10-4)

Safety Data

• Hazardous Substances Data: 443991-10-4(Hazardous Substances Data)

Upstream product

• 773837-37-9 sodium cyanide 
• 97-96-1 2-Ethylbutyraldehyde 
• 17279-30-0 (S)-(-)-α-methylbenzylamine hydrochloride 
• 96-17-3 2-Methylbutyraldehyde 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 151-50-8 potassium cyanide 

Downstream Products

• 443991-11-5 3-ethyl-N²-[(S)-1-phenylethyl]-L-norvalinamide 
• 14328-49-5 3-ethyl-L-norvaline 

Relevant articles and documents

A practical synthesis of 3-ethyl-l-norvaline

An efficient process for the synthesis of 3-ethyl-l-norvaline has been developed. The route makes use of a Strecker reaction, whereby (S)-(-)-α-methylbenzylamine acts as a chiral auxiliary to provide nearly diastereomerically pure α-amino nitrile. Crystal

Production of chirally pure α-amino acids and N-sulfonyl α-amino acids

Methods for production of chirally pure α-amino acids and N-sulfonyl α-amino acids are described. An aldehyde and a cyanide salt are reacted with an α-methylbenzylamine to afford product. The product reacts with a strong acid, neutralized, and extracted.

Heterocyclic sulfonamide inhibitors of beta amyloid production

Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs there