443991-11-5Relevant articles and documents
Substrate-product analogue inhibitors of isoleucine 2-epimerase from: Lactobacillus buchneri by rational design
Sorbara, Noa T.,MacMillan, Joshua W. M.,McCluskey, Gregory D.,Bearne, Stephen L.
, p. 8618 - 8627 (2019/10/02)
A rational approach that may be applied to a broad class of enzyme-catalyzed reactions to design enzyme inhibitors affords a powerful strategy, facilitating the development of drugs and/or molecular probes of enzyme mechanisms. A strategy for the developm
Production of chirally pure α-amino acids and N-sulfonyl α-amino acids
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Page column 22, (2008/06/13)
Methods for production of chirally pure α-amino acids and N-sulfonyl α-amino acids are described. An aldehyde and a cyanide salt are reacted with an α-methylbenzylamine to afford product. The product reacts with a strong acid, neutralized, and extracted.
Heterocyclic sulfonamide inhibitors of beta amyloid production
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, (2008/06/13)
Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs there