444002-57-7

Basic information

• Product Name: N-(4-nitrophenyl)caprolactam
• CAS NO: 444002-57-7
• Molecular Weight: 234.255
• Mol File: 444002-57-7.mol

Chemical Properties

• CAS DataBase Reference: N-(4-nitrophenyl)caprolactam(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-nitrophenyl)caprolactam(444002-57-7)
• EPA Substance Registry System: N-(4-nitrophenyl)caprolactam(444002-57-7)

Safety Data

• Hazardous Substances Data: 444002-57-7(Hazardous Substances Data)

Upstream product

• 105-60-2 caprolactam 
• 636-98-6 p-nitrobenzene iodide 
• 13663-23-5 1-(4-Nitrophenyl)-perhydroazepin 

Downstream Products

• 444002-58-8 1-(4-aminophenyl)-2-caprolactame 

Relevant articles and documents

Efficacy of C-N coupling reactions with a new multinuclear copper complex catalyst and its dissociation into mononuclear species

A new tetranuclear copper(I)-pyridazine (pda)/rhenate hybrid has been synthesized under hydrothermal conditions and structurally characterized by X-ray crystallography. The activity of this catalyst, as well as its dissociation into mononuclear species, was investigated in homogeneous C-N arylation reactions. A variety of N-arylamides and-azoles were synthesized in good to excellent yields, revealing the effect of polynuclear versus mononuclear Cu complexation in this type of coupling reaction.

PROLINE DERIVATIVES

The invention relates to novel compounds of formula (I), wherein X, Y, R1, R2, R3, R4 and n have the meaning cited in claim 1, are inhibitors of the coagulation factor Xa and can be used for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumours.

CARBONYL COMPOUNDS

The invention relates to the novel compounds of formula (I), wherein D, E, G, W, X, Y, T, R and R are defined as in claim 1. The inventive compounds inhibit coagulation factor Xa and can be used in the prophylaxis and/or therapy of thrombo-embolic diseases and for treating tumors.