444083-25-4Relevant academic research and scientific papers
New regiocontrolled synthesis of functionalized pyrroles from 2-azetidinone-tethered allenols
Alcaide, Benito,Almendros, Pedro,Carrascosa, Rocio,Redondo, Maria C.
, p. 637 - 643 (2008/12/21)
A new one-pot approach to synthesize densely substituted racemic and enantiopure pyrroles from β-lactams has been developed. The approach relies on the regiocontrolled cyclization of β-allenamine intermediates derived from the ring opening of 2-azetidinon
Domino metal-free allene-β-lactam-based access to functionalized pyrroles
Alcaide, Benito,Almendros, Pedro,Redondo, María C.
, p. 2616 - 2618 (2008/03/31)
A novel transition metal-free domino reaction sequence in allene-β-lactams, leading to the biologically relevant pyrrole frame has been developed using a sodium methoxide-methanol system. The Royal Society of Chemistry 2006.
New aspects of the indium chemistry of carbonyl-β-lactams
Alcaide, Benito,Almendros, Pedro,Aragoncillo, Cristina,Rodri?guez-Acebes, Raquel
, p. 1163 - 1170 (2007/10/03)
Reactions of racemic as well as optically pure carbonyl-β-lactams with stabilized organo-indium reagents were investigated in aqueous media. The regio- and stereochemistry of the processes were generally good, offering a convenient asymmetric entry to den
Additions of allenyl/propargyl organometallic reagents to 4-oxoazetidine-2-carbaldehydes: Novel palladium-catalyzed domino reactions in allenynes
Alcaide, Benito,Almendros, Pedro,Aragoncillo, Cristina
, p. 1719 - 1729 (2007/10/03)
Metal-mediated carbonyl allenylation and propargylation of 4-oxoazetidine-2-carbaldehydes were investigated in aqueous environment. Different propargyl bromide and metal promoters showed varied regio- and stereoselectivities on product formation. In addit
