444288-00-0

Basic information

• Product Name: N-[2-(2,6-dioxo-piperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-2-phenoxy-acetamide
• CAS NO: 444288-00-0
• Molecular Weight: 407.382
• Mol File: 444288-00-0.mol

Chemical Properties

• CAS DataBase Reference: N-[2-(2,6-dioxo-piperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-2-phenoxy-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(2,6-dioxo-piperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-2-phenoxy-acetamide(444288-00-0)
• EPA Substance Registry System: N-[2-(2,6-dioxo-piperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-2-phenoxy-acetamide(444288-00-0)

Safety Data

• Hazardous Substances Data: 444288-00-0(Hazardous Substances Data)

Upstream product

• 701-99-5 Phenoxyacetyl chloride 
• 19171-19-8 pomalidomide 

Relevant articles and documents

Isoindole-imide compounds, compositions, and uses thereof

The invention relates to isoindole-imide compounds and pharmaceutically acceptable salts, hydrates, solvates, clathrates, enantiomers, diastereomers, racemates, or mixtures of stereoisomers thereof, pharmaceutical compositions comprising these isoindole-imide compounds, and methods for reducing the level of cytokines and their precursors in mammals. In particular, the invention pertains to isoindole-imide compounds that are potent inhibitors of the production of TNF-α in mammals. The isoindole-imides described herein are useful for treating or preventing diseases or disorders in mammals, for example, cancers, such as solid tumors and blood-born tumors; heart disease, such as congestive heart failure; osteoporosis; and genetic, inflammatory; allergic; and autoimmune diseases.